Results 41 to 50 of about 380,756 (310)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Influence of Cutting Angle on Temperature Distribution of Cutter

Shiyou jixie, 2021
The failure of cutter is closely related to cutting temperature, and the formation of cuttings has an impact on the performance and life of cutter. This article builds a rock-breaking mechanics model to conduct numerical simulation analysis on rock ...
Zhang Zaixing, Zhou Qin, Zhang Kai, Li Long, Li Yao   +4 more
doaj  

Pertumbuhan Tanaman Dan Kadar Kalsium Hijauan Sorgum Manis (Sorghum Bicolor (L).moench) Dengan Pemupukan Fosfat Dan Organik (Plant Growth and Calsium Content of Sweet Sorghum Forage (Sorghum Bicolor (L). Moench) with Phosphate and Organic Fertilization) [PDF]

, 2014
The aim of this study was to examine the effect of phosphate and organic fertilization on the growth and calsium (Ca) content of sorghum forage. The materials in this study were sweet sorghum seeds, manure, manure \u27plus\u27 (manure + rock phosphate ...
Benowo, F. E. (Fendias), Karno, K. (Karno), Lukiwati, D. R. (Dwi)   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Study conical pick cutting performance and fatigue life in breaking rock plate process with numerical simulation

Scientific Reports
The fatigue life and cutting performance of conical pick is essential for the roadheader machine in the excavation engineering. In rock breaking process, the rock structural conditions has a certain influence on the rock breaking and rock damage with ...
Mingyan Wang
doaj   +1 more source

GPGPU-parallelised hybrid finite-discrete element modelling of rock chipping and fragmentation process in mechanical cutting

Journal of Rock Mechanics and Geotechnical Engineering, 2020
Mechanical cutting provides one of the most flexible and environmentally friendly excavation methods. It has attracted numerous efforts to model the rock chipping and fragmentation process, especially using the explicit finite element method (FEM) and ...
Mojtaba Mohammadnejad, Sevda Dehkhoda, Daisuke Fukuda, Hongyuan Liu, Andrew Chan   +4 more
doaj   +1 more source

Shear Behavior of Soft Rock Exposed to Alternate Dry and Wet under Constant Stress [PDF]

, 2002
The surface of cutting rock slope has exposed to alternate dry and wet conditions for a long time, and they are weathered. We developed direct shear testing apparatus that can expose soft rock specimen to alternate dry and wet conditions under constant ...
Katae Toshio, Kusumi Harushige, Shiraga Atsushi, 楠見 晴重, 片江 敏雄, 白神 敦   +5 more
core   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source