Results 21 to 30 of about 25,017 (258)

Experimental study on water transfer of soil-rock mixtures under freezing action

open access: yesYantu gongcheng xuebao
The frost-heaving failure of earth-rock dam slopes is mainly caused by the combined action of sand and gravel cushion, frost heaving of dam fills and water migration.
LI Zhuo 1, 2, JIANG Xin 3, ZHANG Jixun 3, ZHAO Yu 3, WANG Yuqing 3, LU Yang 3
doaj   +1 more source

Method for identifying four common rock types of slopes and determining boundary range

open access: yesYantu gongcheng xuebao, 2019
Rock classification and boundary determination of rock slopes are very important for the analysis of slope stability. At present, the artificial methods are inefficient and affected by subjective factors.
WANG Peng-yu , WANG Shu-hong
doaj   +1 more source

Influence of Ground Motion Parameters on the Seismic Response of an Anchored Rock Slope

open access: yesAdvances in Civil Engineering, 2020
The seismic response of rock slopes is closely related to the dynamic characteristics of earthquakes. In this study, based on a numerical model of rock slopes with bolt support, the seismic responses of both anchored and unanchored rock slopes under ...
Ningbo Peng, Yun Dong, Ye Zhu, Jie Hong
doaj   +1 more source

Stability Assessment of the Excavated Rock Slope at the Dagangshan Hydropower Station in China Based on Microseismic Monitoring

open access: yesAdvances in Civil Engineering, 2018
A high-resolution microseismic (MS) monitoring system was implemented at the right bank slope of the Dagangshan hydropower station in May 2010 to analyse the slope stability subjected to continuous excavation.
K. Ma, N. W. Xu, Z. Z. Liang
doaj   +1 more source

Rock Slope Stability Of Ponorogo - Pacitan Road Km 232.5 Using Rock Mass Rating (Rmr) And Rocplane Software

open access: yesRekayasa Sipil, 2021
Geological structures and discontinuities in the rock are weak areas and groundwater infiltration pathways. The existence of geological structures and discontinuities will reduce the level of rock shear strength and the main implication is to increase ...
Hasyim Alhadar   +2 more
doaj   +1 more source

Analysis of Space and Particle Parameter Influence to Stability of Soil-rock Mixture Slope

open access: yes工程科学与技术, 2020
The soil-rock mixture slope has the characteristics of complex physical and mechanical properties and strong nonlinearity, which is greatly affected by geometric factors such as the rock distribution and rock particle size.
Xinyao ZHAO   +3 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Sandstone Slope Stability Analysis Under Wetting-Drying Cycles Based on Generalized Hoek-Brown Failure Criterion

open access: yesFrontiers in Earth Science, 2022
The deterioration of rock strength due to cyclic fluctuations in the groundwater level in drawdown regions influences bank slope stability. Based on wetting–drying cycling and uniaxial compression tests of sandstone specimens, the intact rock strength ...
Kai Kang   +5 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Displacement Measurements and Numerical Analysis of Long-Term Rock Slope Deformation at Higashi-Shikagoe Limestone Quarry, Japan

open access: yesAdvances in Civil Engineering, 2021
The Higashi-Shikagoe limestone quarry is an open-pit mine situated in Hokkaido Prefecture, Japan, that has experienced four slope failure incidents since 1996.
Clement A. Amagu   +8 more
doaj   +1 more source

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