Sugammadex and rocuronium-induced anaphylaxis [PDF]
Perioperative anaphylaxis is a life-threatening clinical condition that is typically the result of drugs or substances used for anesthesia or surgery. The most common cause of anaphylaxis during anesthesia is reportedly neuromuscular blocking agents.
T. Takazawa, H. Mitsuhata, P. Mertes
semanticscholar +4 more sources
Effects of rocuronium, sugammadex and rocuronium-sugammadex complex on coagulation in rats [PDF]
Background and objectives: Sugammadex is an alternative pharmacological drug capable of reversing neuromuscular blockades without the limitations that are presented by anticholinesterase drugs.
Ismar Lima Cavalcanti+6 more
doaj +11 more sources
Anaphylaxis to rocuronium [PDF]
Reports about anaphylactic and anaphylactoid reactions to rocuronium have increased recently. We report two new cases of documented grade III anaphylaxis, leading to death in one patient. The first case occurred in an 81-year-old ASA II woman scheduled for emergency abdominal surgery.
Christophe Baillard+6 more
openalex +4 more sources
Pharmacological interventions for acceleration of the onset time of rocuronium: a meta-analysis. [PDF]
Rocuronium is an acceptable alternative when succinylcholine is contraindicated for facilitating the endotracheal intubation. However, the onset time of rocuronium for good intubation condition is still slower than that condition of succinylcholine. This
Jing Dong+4 more
doaj +1 more source
Pain on Injection of Rocuronium Bromide
Girish P. Joshi, Charles W. Whitten
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The antagonistic effect of neostigmine on rocuronium-, clindamycin-, or both-induced neuromuscular blocking in the rat phrenic nerve-hemidiaphragm [PDF]
BackgroundNeostigmine augments clindamycin-induced neuromuscular block and antagonizes rocuronium-induced neuromuscular block; however, it remains unclear whether neostigmine enhances the neuromuscular blocking (NMB) that is caused by combinations of ...
Seung Soo Kim+3 more
doaj +1 more source
Successful management of rocuronium-induced anaphylaxis with sugammadex: A case report
Although anaphylaxis during anaesthesia is a rare event, neuromuscular blocking drugs are responsible for 62% of anaesthesia-related anaphylaxis. However, sugammadex, a modified gamma-cyclodextrin, can encapsulate rocuronium molecules and cause the rapid
Sheng-Kai Hung+4 more
doaj +1 more source
Comparison of Intubating Conditions of Two Doses of Rocuronium Bromide with Succinylcholine in Children undergoing Elective Surgeries under General Anaesthesia- A Randomised Control Trial [PDF]
Introduction: Succinylcholine is a muscle relaxant of choice for paediatric intubation due to its fast onset and ultrashort duration of action but it is associated with unwanted side-effects.
Maitri Patel+4 more
doaj +1 more source
The effect of long-term oral dantrolene on the neuromuscular action of rocuronium: a case report [PDF]
Oral dantrolene causes a dose-dependent depression of skeletal muscle contractility. A 52-year-old man treated with oral dantrolene for spasticity after spinal cord injury was scheduled to undergo irrigation and drainage of a thigh abscess under general ...
Jinwoo Jeon+4 more
doaj +1 more source