A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J+2 more
core +2 more sources
Kounis Syndrome Associated With Selective Anaphylaxis to Cefazolin. [PDF]
info:eu-repo/semantics ...
Chambel, M+5 more
core +1 more source
Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]
Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E.+2 more
core +2 more sources
Rocuronium and malignant hyperthermia
Beggs et al.[1][1] presented two interesting case reports postulating an association between rocuronium and malignant hyperthermia (MH). Although the observed fever in these patients declined after discontinuation of rocuronium, several points need further discussion.
Frank Schuster, Stephan Johannsen
openaire +7 more sources
Pharmacodynamic behaviour of rocuronium in the elderly [PDF]
This study compared the potency and time course of action of rocuronium (ORG 9426) in elderly and young patients during nitrous oxide-opioid anaesthesia. One hundred ASA physical status I-II patients (60, aged 65-80 yr, and 40, aged 20-45 yr) were studied by measuring the force of contraction of the adductor pollicis in response to train-of-four ...
François Donati+5 more
openaire +3 more sources
Effects of 2 mg.kg−1 of Intravenous Lidocaine on the Latency of Two Different Doses of Rocuronium and on the Hemodynamic Response to Orotracheal Intubation [PDF]
SummaryBackground and objectivesLidocaine potentiates the effects of neuromuscular blockers and attenuates the hemodynamic response to orotracheal intubation.
Garcia, Luís Vicente+2 more
core +1 more source
The effect of palonosetron on rocuronium-induced withdrawal movement [PDF]
BackgroundRocuronium causes pain and withdrawal movement during induction of anesthesia. In this study, palonosetron was investigated to have analgesic effect on the reduction of rocuronium-induced withdrawal movement.Methods120 patients were randomly ...
Chung, Seung-Yeon+5 more
core +3 more sources
Mrgprx2 Activation by Rocuronium: Insights From Studies with Human Skin Mast Cells and Missense Variants [PDF]
Perioperative hypersensitivity (POH) to the neuromuscular blocking drug (NMBD) rocuronium was previously thought to be IgE and mast cell (MC)-mediated. However, the recent seminalobservation that rocuronium induces degranulation in murine peritoneal MCs (
Ali, H.+4 more
core +2 more sources
Succinylcholine versus rocuronium for rapid sequence intubation in intensive care: a prospective, randomized controlled trial [PDF]
Succinylcholine and rocuronium are widely used to facilitate rapid sequence induction (RSI) intubation in intensive care. Concerns relate to the side effects of succinylcholine and to slower onset and inferior intubation conditions associated with ...
Aebi, Timothy+7 more
core +2 more sources
ABSTRACT Objective To describe perinatal and short‐term pediatric outcomes and procedural safety of fetal endoscopic tracheal occlusion (FETO) in a Canadian national referral centre. Methods Retrospective study including all consecutive FETO cases at the Ontario Fetal Centre between 2010 and 2024.
Yada Kunpalin+10 more
wiley +1 more source