Results 11 to 20 of about 37,671 (280)

MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants

Cells, 2021
Perioperative hypersensitivity (POH) to the neuromuscular blocking drug (NMBD) rocuronium was previously thought to be IgE and mast cell (MC)-mediated. However, the recent seminal observation that rocuronium induces degranulation in murine peritoneal MCs
Chalatip Chompunud Na Ayudhya, Aetas Amponnawarat, Saptarshi Roy, Carole A. Oskeritzian, Hydar Ali   +4 more
doaj   +2 more sources

Prolonged onset and duration of action of rocuronium after accidental subcutaneous injection in a patient with chronic renal failure—a case report

JA Clinical Reports, 2021
Background Drugs administered subcutaneously have delayed onset and prolonged duration of action versus those given intravenously. Since the duration of action of rocuronium is prolonged in patients with renal dysfunction, subcutaneous administration of ...
Akira Doshu-Kajiura, Junko Suzuki, Takahiro Suzuki   +2 more
doaj   +2 more sources

Life-threatening rocuronium-induced anaphylactic shock without cutaneous manifestations successfully reversed with sugammadex: a case report

JA Clinical Reports, 2020
Background Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been ...
Yoshiaki Takise, Jungo Kato, Tomohiro Suhara, Takashige Yamada, Takeru Funakoshi, Hayato Takahashi, Masayuki Amagai, Hiroshi Morisaki   +7 more
doaj   +2 more sources

Sugammadex versus neostigmine after rocuronium continuous infusion in patients undergoing liver transplantation. [PDF]

BMC Anesthesiology, 2020
Background Rapid neuromuscular block reversal at the end of major abdominal surgery is recommended to avoid any postoperative residual block. To date, no study has evaluated sugammadex performance after rocuronium administration in patients undergoing ...
Cristian Deana, Federico Barbariol, Stefano D’Incà, Livia Pompei, Giorgio Della Rocca   +4 more
openalex   +2 more sources

On-demand versus continuous rocuronium infusion for deep neuromuscular relaxation in patients undergoing thoraco-laparoscopic esophagectomy: a randomized-controlled clinical trial (DEPTH) [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2019
PurposeDeep neuromuscular blockade (NMB) can improve surgical conditions and possibly pain after low-risk laparoscopic surgery. We hypothesized that targeting a deep level of NMB by a continuous compared with an on-demand infusion of rocuronium could ...
Denise P. Veelo, Suzanne S. Gisbertz, Jan M. Binnekade, Rebekka A. Hannivoort, Johanneke A. Bosman, Bart F. Geerts, Manfred Blobner, Mark I. van Berge Henegouwen, Markus W. Hollmann   +8 more
openalex   +2 more sources

A Dose-finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis

Anesthesiology, 2023
Background: The dose of sugammadex recommended by the manufacturer for reversal of rocuronium is 2 mg/kg when the train-of-four count is 2 or more and 4 mg/kg when it is less than 2 but there is a posttetanic count of at least 1. The purpose of this dose-
T. Bowdle, Kishanee Haththotuwegama, S. Jelacic, Sharon T. Nguyen, K. Togashi, K. Michaelsen   +5 more
semanticscholar   +1 more source

Anesthesia Management via an Automated Control System for Propofol, Remifentanil, and Rocuronium Compared to Management by Anesthesiologists: An Investigator-Initiated Study

Journal of Clinical Medicine, 2023
Background: We previously developed an automated total intravenous anesthesia control system that uses new closed-loop system algorithms to administer propofol, remifentanil, and rocuronium based on the bispectral index and train-of-four data.
Osamu Nagata, Y. Matsuki, Shuko Matsuda, Keita Hazama, Saiko Fukunaga, Hideki Nakatsuka, Fumiyo Yasuma, Yasuhiro Maehara, Shoko Fujioka, Karin Tajima, Ichiro Kondo, Itaru Ginoza, Misuzu Hayashi, Manabu Kakinohana, Kenji Shigemi   +14 more
semanticscholar   +1 more source

Mechanisms contributing to hypotension after anesthetic induction with sufentanil, propofol, and rocuronium: a prospective observational study

Journal of clinical monitoring and computing, 2021
It remains unclear whether reduced myocardial contractility, venous dilation with decreased venous return, or arterial dilation with reduced systemic vascular resistance contribute most to hypotension after induction of general anesthesia.
B. Saugel, Elisa-Johanna Bebert, L. Briesenick, Phillip Hoppe, G. Greiwe, Dongsheng Yang, C. Ma, E. Mascha, D. Sessler, Dorothea E. Rogge   +9 more
semanticscholar   +1 more source

Rocuronium Versus Succinylcholine in Patients With Acute Myocardial Infarction Requiring Mechanical Ventilation

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2023
atients with acute myocardial infarction (AMI) who require invasive mechanical ventilation (IMV) are a critically ill patient population with a high risk of mortality.
BS ChristopherSchenck, MD Soumya Banna, PharmD Bcccp Cory Heck, Mba Tariq Ali MD, Mhs P. Elliott Miller MD, M. M. P. Elliott Miller, MD Julie K. Freed   +6 more
semanticscholar   +1 more source

High-dose rocuronium-induced paralysis of the adductor pollicis muscle facilitates detection of the timing for tracheal intubation in elderly patients: a randomized double-blind study [PDF]

Journal of Anesthesia, 2020
To prevent coughing related to tracheal intubation and the resultant exposure of intubating staff to the patients’ expiratory aerosols, the timing of tracheal intubation needs to be precisely predicted.
Shunichi Takagi, Nami Sugaya, Naoto Kiuchi, Aya Iwasa, Masumi Itagaki, Aya Seki, Junko Suzuki, Takahiro Suzuki   +7 more
openalex   +2 more sources