Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao+16 more
wiley +1 more source
Plague and tularemia surveillance in hormozgan province, Southern Iran. [PDF]
Cohan HA+7 more
europepmc +1 more source
An Amygdala‐hippocampus Circuit for Endocannabinoid Modulation of Anxiety Avoidance
This study employs three synapse‐specific endocannabinoids (eCB) probes to monitor dynamic eCB release, activate CB1Rs and knockdown 2‐AG biosynthesis enzymes in glutamatergic anterior basolateral amygdala ‐ ventral hippocampus (aBLA–vHPC) circuit. At aBLA–vHPC circuits, activation of CB1Rs reduce anxiety avoidance, and knockdown of eCB biosynthesis ...
Bao Xue+9 more
wiley +1 more source
Verifying interruption of transmission or elimination of Schistosoma japonicum must consider schistosome infections in wild rodents. [PDF]
Xu Q+4 more
europepmc +1 more source
The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease [PDF]
Christa L. Blenck+3 more
openalex +1 more source
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang+13 more
wiley +1 more source
Influence of natural and anthropogenic drivers on plague risk in Southwest China: A multicenter cross-sectional study. [PDF]
Lou Z+9 more
europepmc +1 more source
Evidence for Personal Protective Measures to Reduce Human Contact With Blacklegged Ticks and for Environmentally Based Control Methods to Suppress Host-Seeking Blacklegged Ticks and Reduce Infection with Lyme Disease Spirochetes in Tick Vectors and Rodent Reservoirs [PDF]
Lars Eisen, Marc C. Dolan
openalex +1 more source
Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart+4 more
wiley +1 more source
Chasing intermediate hosts of <i>Echinococcus multilocularis</i> at the southern edge of its European distribution using red fox stomach content analysis. [PDF]
Salvatore Andrea C+9 more
europepmc +1 more source