Results 91 to 100 of about 566,311 (275)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Edukasia, 2023 The existence of bullying behavior in schools is certainly a scourge for educational units. With this research, namely applying the role playing method to class VII students at TanjungBalai 4 Public Middle School for the 2023-2024 academic year, this ...
Stariah, Ahmad Syarqawi
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
RPGs to enhance the second language acquisition of both Mandarin and English [PDF]
, 2019 Research Question: “To what degree can it be evidenced that interactive role playing games enhance the mutual second language acquisition of both Mandarin and English?”♦ Small scale side project to ascertain avatar interaction preferences based on ...
Dempster, Euan W., Harbord, Charly
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Pengaruh Model Role Playing Terhadap Kemampuan Berbalas Pantun Siswa Kelas X SMA Parulian 2 Medan Tahun Pembelajaran 2013/2014 [PDF]
, 2014 Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran role playing terhadap kemampuan siswa berbalas pantun siswa kelas X SMA Parulian 2 Medan tahun pembelajaran 2013/2014. Populasi penelitian ini adalah seluruh siswa kelas X SMA Parulian
silalahi, N. (Nurtani)
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cakrawala: Jurnal Pendidikan, 2011 Guru harus membuat perencanaan yang strategis sebelum pembelajaran berlangsung dengan harapan pembelajaran dapat mencapai target optimal dengan pengembangan menggunakan strategi role playing berbasis analisis SWOT agar menciptakan prestasi belajar yang ...
Ibnu Sina
doaj +1 more source
Model Pembelajaran Role Playing pada Mata Pelajaran Pkn untuk Meningkatkan Motivasi Belajar [PDF]
, 2015 This research is aimed to describe and to know: (1) The process of applying PKn learning by applying role playing model, (2) Increasing student learning motivation by role playing model, (3) Pkns learning completeness students.
Sudjarwo, S. (Sudjarwo) +2 more
core +2 more sources