Results 101 to 110 of about 3,138,985 (315)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The emergent roles of a designer in the development of an e learning service [PDF]

open access: yes, 2009
This paper presents reflections from a service design case study and uses it to investigate the emerging roles of a designer. Skills, methodologies and values are drawn through the case study and used to communicate how this contributes to the continuing
Yee, Joyce   +2 more
core  

New roles for EPHB4 in prostate cancer [PDF]

open access: yes, 2016
This thesis presents insight into the signalling pathways of EphB4, a protein known to be involved in cancer progression. A new method was developed and used to identify a number of proteins that can interact with EphB4; and a novel mechanism of action ...
Rutkowski, Raphael C.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Life course social roles and women's health in mid-life: causation or selection? [PDF]

open access: yes, 2006
Study objective: To investigate whether relations between social roles and health are explained by health selection into employment and parenthood by examining the influence of early health on relations between long term social role histories and health ...
Bartley, M, Hardy, R, McMunn, A, Kuh, D
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Responsibility Subjects: Roles and Gender Stereotypes in Discourses about Contraception and Contraceptive Responsibility among Students at the San Juan Bautista de La Salle Educational Institution in Medellín [PDF]

open access: yes
En Colombia, a pesar de los avances en materia de igualdad de género y derechos sexuales y reproductivos, persisten discursos que posicionan a las mujeres como responsables de la anticoncepción.
Gutiérrez Martínez, Cristian David
core   +2 more sources

Medical student involvement in health policy roles [PDF]

open access: yes, 2017
Bassit Malik,1 Utkarsh Ojha,1 Hassan Khan,1 Farzana Begum,2 Harun Khan,1 Qasim Malik3 1School of Medicine, Imperial College London, London, UK; 2Barts and the London School of Medicine and Dentistry, London, UK; 3Heart of England NHS Foundation Trust ...
Bassit Malik   +16 more
core   +1 more source

Rum for kvalifikation, plads til inklusion? - om mødet mellem børn, rum og pædagogik i den danske folkeskole

open access: yesNordisk tidsskrift for pedagogikk og kritikk, 2016
The research question in this article is: What spaces and roles do pedagogues create in the tension between qualification and inclusion after the school reform in Denmark in 2014?
David Thore Gravesen, Lea Ringskou
doaj   +1 more source

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