Results 111 to 120 of about 6,905,317 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Situation Recognition with Graph Neural Networks

, 2017
We address the problem of recognizing situations in images. Given an image, the task is to predict the most salient verb (action), and fill its semantic roles such as who is performing the action, what is the source and target of the action, etc ...
Fidler, Sanja, Jia, Jiaya, Li, Ruiyu, Liao, Renjie, Tapaswi, Makarand, Urtasun, Raquel   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Policy based roles for distributed systems security

, 1997
Distributed systems are increasingly being used in commercial environments necessitating the development of trustworthy and reliable security mechanisms. There is often no clear informal or formal specification of enterprise authorisation policies and no
Lupu,E.C.,, Sloman,M.S.,, Yialelis,N.,
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Fracturas psicosociales asociadas a la prejubilación [PDF]

Aposta, 2010
Este artículo analiza, de una manera introductoria, el concepto de prejubilación. A partir de una perspectiva psicosocial, se señalan los problemas derivados de esa expulsión prematura del mercado laboral que padecen personas mayores de cincuenta y cinco
Héctor Tejón Sáez
doaj  

Global roles of currencies [PDF]

This paper presents a new concept – the global roles of currencies. The concept combines the domestic and international (cross-border) use of currencies and therefore captures the overall importance of different currencies in a globalised economy.
Thimann, Christian
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Effects of Advertising on Gender Roles within American Marriages [PDF]

, 2012
The following literature review is designed to explore existing scholarly literature addressing the effect of advertising on marriages in American society. Marriage is an ever-present, ever-evolving social structure, and as such, it is an important topic
Browall, Victoria
core   +2 more sources