Results 121 to 130 of about 17,943,461 (336)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Determining the level of high-speed abilities of young soccer players aged from 10 to 12 years
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013 The problems of high-speed training of young players were considered. Carried out an analytical review of the scientific literature on the specific sources of development and control the speed of the players.
S.I. Lebedev
doaj
Rôles des mangroves, modes et perspectives de gestion au Delta du Saloum (Sénégal)
VertigO, 2016 This study allowed determining diverse roles of the mangrove in Delta du Saloum. To the ecological plan, the slightest environmental changes are harmful to mangrove (Ndour, 2005 ; Thomas and al., 1997 ; Blasco, 1983).
Ngor Ndour +2 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Laboreal, 2011 This article stresses in workload increase processes derived from operational strategies that organizational actors develop spontaneously. Such processes tend to be produced when roles, organizational regulations and/or artifacts which support work ...
Carlos Díaz Canepa
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Competency Implications of Changing Human Resource Roles [PDF]
, 1994 [Excerpt] The present study examines which competencies will be necessary to perform key human resource roles over the next decade at Eastman Kodak Company.
Blancero, Donna +2 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Many Roles of an Academic Surgeon [PDF]
, 2017 One of our most important responsibilities is training the next generation of fellows, residents, medical students, and undergraduate students aspiring to a career in medicine.
Yeo, MD, FACS, Charles J.
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