Results 71 to 80 of about 266,284 (255)
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Adhesion Control Method for EMU
Chengshi guidao jiaotong yanjiuObjective Given the high operating speeds, minimal residual acceleration margin, and open-air track conditions of EMU (electric multiple units), as well as the deficiencies in conventional combination correction methods such as poor accuracy in criterion
MA Fayun +5 more
doaj +1 more source
Re-scheduling in railways: the rolling stock balancing problem [PDF]
This paper addresses the Rolling Stock Balancing Problem (RSBP). This problem arises at a passenger railway operator when the rolling stock has to be re-scheduled due to changing circumstances. These problems arise both in the planning process and during
Budai-Balke, G. +4 more
core +1 more source
Importance and applications of robotic and autonomous systems (RAS) in railway maintenance sector: a review [PDF]
, 2019 Maintenance, which is critical for safe, reliable, quality, and cost-effective service, plays a dominant role in the railway industry. Therefore, this paper examines the importance and applications of Robotic and Autonomous Systems (RAS) in railway ...
Ackerman +6 more
core +3 more sources
A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application
Advanced Science, EarlyView.This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu +5 more
wiley +1 more source
Efficient Circulation of Railway Rolling Stock [PDF]
, 2002 Railway rolling stock (locomotives, carriages, and train units) is one of the most significant cost sources for operatorsof passenger trains, both public and private.
Alfieri, A. (Arianna) +3 more
core
Wear rates in urban rail systems [PDF]
, 2017 A significant part of maintenance costs in urban rail systems (metro, tram, light rapid transit/light metro) is due to wheel-rail wear. Wear rates - measured for example as depth of wear per kilometre run (rolling stock) or per train passage (rails ...
Licciardello, R. +3 more
core +1 more source
An Integrated NLP‐ML Framework for Property Prediction and Design of Steels
Advanced Science, EarlyView.This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju +5 more
wiley +1 more source
Influence of impact forces on the strength characteristics of the railway roadbed
Вестник Научно-исследовательского института железнодорожного транспорта, 2017 The article presents the results of studies on the influence of impact forces on the strength characteristics of the soil of the main site of the roadbed (MSRB). It is shown that impulsive shock forces of 360 ...
O. G. Krasnov, N. N. Astanin
doaj +1 more source
Determinants of Rolling Stock Maintenance Cost in Metros
, 2015 This study examines the economies of scale and the determinants of rolling stock maintenance costs for 24 urban rail transit operators. The estimates reveal significant returns to scale in maintenance for both per car and per car kilometre.
Anderson, RJ, Brage-Ardao, R, Graham, DJ
core +1 more source