Results 71 to 80 of about 295,445 (314)
Public Opinion and National Prestige: The Politics of Canadian Army Participation to the Invasion of Sicily, 1942–1943 [PDF]
, 2012 The participation of Canadian troops in the Sicilian campaign of July and August 1943 marked a distinctive shift in Canada’s war policy, and significantly influenced the employment of the army until the end of hostilities in May 1945.
Barton, Brandey
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
«The Big Three» (J. Stalin, F. Roosevelt, W. Churchill): Allies for the Peace
Vestnik RUDN. International Relations, 2015 The article is dedicated to the asset of the Big Three - J. Stalin, F.D. Roosevelt and W. Churchill - to victory over Nazi Germany and safeguarding of comprehensive peace.
L V Ponomarenko, O S Chikrizova
doaj
Special Libraries, March 1959 [PDF]
, 1958 Volume 50, Issue 3https://scholarworks.sjsu.edu/sla_sl_1959/1002/thumbnail ...
Special Libraries Association
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]
, 2017 BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo +6 more
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
"The prince of all the rookies :" remaking working class masculinity and heroism in Traffic in Souls [PDF]
, 2015 textThis paper seeks to explore the role evolving masculinities played in the Progressive Era's white slavery panic through one of the period's most popular films: George Loane Tucker's Traffic in Souls and its ensuing novelization by Eustace Hale Ball ...
Cotter, Erin June
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