Results 91 to 100 of about 1,671,483 (282)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
VIIRS On-Orbit Optical Anomaly - Investigation, Analysis, Root Cause Determination and Lessons Learned [PDF]
, 2012 A gradual, but persistent, decrease in the optical throughput was detected during the early commissioning phase for the Suomi National Polar-Orbiting Partnership (SNPP) Visible Infrared Imager Radiometer Suite (VIIRS) Near Infrared (NIR) bands.
Butler, James +9 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Marketing Strategy for New Venture in Information Technology Education (Online Tutorial – TUTON) [PDF]
, 2013 Indonesia has a rapid development in Information Technology (IT) as well as the public interest to learn it. However, to find qualified employee in IT is difficult, they often lacks proper education in IT background. IT education is not only need quality,
Larso, D. (Dwi), Lubis, E. H. (Esty)
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Root cause analysis and health informatics [PDF]
Root Cause Analysis (RCA) is the most widely used system analysis tool for investigating safety related incidents in healthcare. This contribution reviews RCA techniques, using a Health Informatics example, and discusses barriers to their successful ...
Despotou, George, Jones, Richard W.
core
Reducing Late-Timing Failure at Scale: Straggler Root-Cause Analysis in Cloud Datacenters [PDF]
, 2016 Task stragglers hinder effective parallel job execution in Cloud datacenters, resulting in late-timing failures due to the violation of specified timing constraints.
Garraghan, P +4 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Iranian Journal of Nursing and Midwifery Research, 2015 Background: Many maternal deaths caused are due to preventable causes during pregnancy and childbirth. Therefore, the detailed analysis of the root causes provides developing a plan and appropriate interventions to prevent these deaths occurring in the ...
Marjan Beigi +4 more
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