Results 61 to 70 of about 1,075,947 (278)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Host genetics influences the root microbiome of Pinus radiata [PDF]

Background and Aims:Root microbiomes can benefit the health and fitness of host plants but manipulating them artificially has challenges. Instead, manipulating the host species through breeding can indirectly promote the development of a beneficial root ...
Day, Nicola J., Graham, Natalie J., Slavov, Gancho T., Wakelin, Steve A.   +3 more
core   +1 more source

Characterizing both bacteria and fungi improves understanding of the Arabidopsis root microbiome [PDF]

, 2019
Roots provide plants mineral nutrients and stability in soil; while doing so, they come into contact with diverse soil microbes that affect plant health and productivity.
Horton, Matthew W, Mittelstrass, Jana, Bergelson, Joy   +2 more
core   +1 more source

Exploring the Role of Vertical and Horizontal Pathways in the Formation of Lettuce Plant Endospheric Bacterial Communities: A Comparative Study of Hydroponic and Soil Systems

Horticulturae
Plant-associated microbiomes play a critical role in plant health, nutrition, growth, and adaptation. This study aimed to investigate the formation pathways of the endospheric microbiome in lettuce (Lactuca sativa) through vertical (seed) and horizontal (
Polina Kuryntseva, Nataliya Pronovich, Gulnaz Galieva, Polina Galitskaya, Svetlana Selivanovskaya   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Comparative analysis of microbiome in coronal and root caries [PDF]

BMC Oral Health
Abstract Background The global rise in the elderly population has increased the prevalence of root caries. Streptococcus mutans, Lactobacilli and Actinomyces are considered the primary pathogens of dental caries in culture-based studies.
Gondo, Tadamu, Hiraishi, Noriko, Takeuchi, Azusa, Moyes, David; id_orcid 0000-0002-1657-918X, Shimada, Yasushi   +4 more
openaire   +3 more sources

Identification of plant genotype dependent microbiome recruitment associated with disease resistance against root rot in peas [PDF]

, 2023
The cultivation of pea (Pisum sativum) is highly constrained by various soil-borne pathogens. Together these pathogens form a pea root rot complex (PRRC) and trigger soil fatigue.
Temme, Nora, Messmer, Monika, Hartmann, Martin, Kussmann, Sebastian, Schneider, Michael, Horton, Matthew W., Studer, Bruno, Hohmann, Pierre, Ariza Suarez, Daniel, Oldach, Klaus, Gfeller, Valentin, Bodenhausen, Natacha, Wille, Lukas   +12 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Rhizobium Symbiotic Capacity Shapes Root-Associated Microbiomes in Soybean [PDF]

, 2021
Root-microbiome interactions are of central importance for plant performance and yield. A distinctive feature of legumes is that they engage in symbiosis with N-2-fixing rhizobia.
Xu, Jianming, Hu, Lingfei, Zhang, Yunzeng, Schlaeppi, Klaus, Lu, Zhijiang, Chen, Wenfeng, Lu, Yuanhui, Zhao, Kankan, Erb, Matthias, Stirling, Erinne, Ye, Shudi, Liu, Yuanhui, Wang, Entao, Ma, Bin, Wenfeng Chen, Yuanhui Liu, Kankan Zhao, Lingfei Hu, Matthias Erb, Bin Ma, Shudi Ye, Entao Wang, Yunzeng Zhang, Jianming Xu, Zhijiang Lu, Erinne Stirling, Klaus Schlaeppi   +26 more
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source