Results 111 to 120 of about 2,237,927 (278)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Root Systems of Five Clonal Avocado Genotypes

Horticulturae
The root system of clonal rootstocks has been poorly studied, despite its crucial importance. Roots not only provide support and nutrition to the plant but also contribute to tolerance to pests, diseases and environmental stresses, in addition to ...
Nancy Elena Gonzalez-Florez, Alejandro Facundo Barrientos-Priego, Eduardo Campos-Rojas, María Teresa Beryl Colinas y León, Prometeo Sánchez García   +4 more
doaj   +1 more source

Rhizoboxes as Rapid Tools for the Study of Root Systems of Prunus Seedlings. [PDF]

Plants (Basel), 2022
Lesmes-Vesga RA, Cano LM, Ritenour MA, Sarkhosh A, Chaparro JX, Rossi L.   +5 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A modified aeroponic system for growing small-seeded legumes and other plants to study root systems. [PDF]

Plant Methods, 2023
Cai J, Veerappan V, Arildsen K, Sullivan C, Piechowicz M, Frugoli J, Dickstein R.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fine-root morphology in cacao-based systems responds to soil penetration resistance rather than macroporosity

Acta Agriculturae Scandinavica. Section B, Soil and Plant Science
Fine root morphology plays a key role in helping perennial crops like cacao (Theobroma cacao) cope with compacted soil conditions. However, how soil physical constraints such as penetration resistance and macroporosity influence fine root traits in ...
Danny Dwi Saputra, Rika Ratna Sari
doaj   +1 more source

Correction: A modified aeroponic system for growing small-seeded legumes and other plants to study root systems. [PDF]

Plant Methods, 2023
Cai J, Veerappan V, Arildsen K, Sullivan C, Piechowicz M, Frugoli J, Dickstein R.   +6 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

3D segmentation of plant root systems using spatial pyramid pooling and locally adaptive field-of-view inference. [PDF]

Front Plant Sci, 2023
Alle J, Gruber R, Wörlein N, Uhlmann N, Claußen J, Wittenberg T, Gerth S.   +6 more
europepmc   +1 more source