Results 161 to 170 of about 2,237,927 (278)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Whole-genome sequences of 38 siderophore-producing isolates from root systems of two pea and one wheat varieties. [PDF]

Microbiol Resour Announc
Zhu L, Lopez-Roques C, Sallaberry M, Jason K, Ouerdane L, Mazurier S, Lemanceau P, Pivato B.   +7 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Advancing hyperspectral imaging techniques for root systems: a new pipeline for macro- and microscale image acquisition and classification. [PDF]

Plant Methods
Faehn C, Konert G, Keinänen M, Karppinen K, Krause K.   +4 more
europepmc   +1 more source

The Plasticity of Root Systems in Response to External Phosphate. [PDF]

Int J Mol Sci, 2020
Huang G, Zhang D.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The impact of abandoned iron ore on the endophytic bacterial communities and functions in the root systems of three major crops in the local area. [PDF]

Front Microbiol
Chen S, Tang J, Xu J, Peng L, Wu P, Li Q.   +5 more
europepmc   +1 more source

Tillage and irrigation increase wheat root systems at deep soil layer and grain yields in lime concretion black soil. [PDF]

Sci Rep, 2021
Wang J, Wang Z, Gu F, Liu H, Kang G, Feng W, Wang Y, Guo T.   +7 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Research on Fine-Grained Phenotypic Analysis of Temporal Root Systems - Improved YoloV8seg Applied for Fine-Grained Analysis of In Situ Root Temporal Phenotypes. [PDF]

Adv Sci (Weinh)
Yu Q, Zhang M, Wang L, Liu X, Zhu L, Liu L, Wang N.   +6 more
europepmc   +1 more source