Results 101 to 110 of about 989,542 (371)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Root subsystems of rank 2 hyperbolic root systems [PDF]
arXiv, 2015 Let $\Delta$ be a rank 2 hyperbolic root system. Then $\Delta$ has generalized Cartan matrix $H(a,b)= \left(\begin{smallmatrix} ~2 & -b\\ -a & ~2 \end{smallmatrix}\right)$ indexed by $a,b\in\mathbb{Z}$ with $ab\geq 5$. If $a\neq b$, then $\Delta$ is non-symmetric and is generated by one long simple root and one short simple root; whereas if $a= b ...
arxiv
Sampling roots to capture plant and soil functions
, 2017 Summary Roots vary in anatomy, morphology and physiology, both spatially (different parts of the same root system) and temporally (plastic changes, root ageing), suggesting that root trait measurements are strongly affected by root sampling categories.
G. T. Freschet, C. Roumet
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Root polytopes and growth series of root lattices [PDF]
SIAM Journal on Discrete Mathematics 25 (2011), 360-378, 2008 The convex hull of the roots of a classical root lattice is called a root polytope. We determine explicit unimodular triangulations of the boundaries of the root polytopes associated to the root lattices A_n, C_n, and D_n, and compute their f-and h-vectors. This leads us to recover formulae for the growth series of these root lattices, which were first
arxiv
Root operators, root groups and retractions [PDF]
Journal of Combinatorial Algebra, 2018 We prove that the Gaussent–Littelmann root operators on galleries can be expressed purely in terms of retractions of a (Bruhat–Tits) building. In addition we establish a connection to the root datum at infinity.
openaire +3 more sources
Curcumol: From Plant Roots to Cancer Roots
International Journal on Biological Sciences, 2019 Natural products, an infinite treasure of bioactive scaffolds, have provided an excellent reservoir for the discovery of drugs since millennium. These naturally occurring, biologically active and therapeutically effective chemical entities have emerged ...
Wei Wei +11 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A Formidable Task: Reflections on obtaining legal empirical evidence on human trafficking in Canada
Anti-Trafficking Review, 2017 This article explores the experiences, challenges and findings of two empirical research studies examining Canada’s legal efforts to combat human trafficking.
Hayli Millar +2 more
doaj +1 more source