Results 151 to 160 of about 2,572,208 (344)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Catechin is a phytototoxin and a pro-oxidant secreted from the roots of Centaurea stoebe [PDF]
, 2010 Shail Kaushik +3 more
openalex +1 more source
Acute Oral Toxicity Study of Ethyl Acetate Extracts of Ficus benghalensis Aerial Roots
, 2023 Anand Ramasamy, K. Kathiresan
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Morphogenetic Influence of (CO2 + HCO3−) on Roots [PDF]
, 1963 Carsten Geisler
openalex +1 more source
Observations of the Roots of Plasma Bubbles: Are they sometimes foamy? [PDF]
, 2023 C. L. Bennett
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
At the Roots of Causality: Ontology and Aetiology from Avicenna to Fakhr al-Dīn al-Rāzī by Francesco Omar Zamboni (review) [PDF]
Damien Janos
openalex +1 more source