Results 11 to 20 of about 27,133 (207)

The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity

Artificial Cells, Nanomedicine and Biotechnology, 2019
Ropivacaine is a commonly used local anaesthetic, but its side effects remain largely unknown. In the present study, we investigated the side effects of ropivacaine in human neuronal SH-5Y5Y cells. We show that 0.5% and 1% ropivacaine could cause fission-
Yan Chen, Lili Yan, Yan Zhang, Xianhui Yang   +3 more
exaly   +3 more sources

Dexmedetomidine Prolongs the Duration of Ropivacaine Corneal Anesthesia After Subconjunctival Injection in Healthy Horses. [PDF]

Vet Ophthalmol
ABSTRACT Objective To determine whether dexmedetomidine prolongs corneal anesthesia following subconjunctival ropivacaine injection in healthy equine eyes. Methods Ten horses with normal ophthalmic exams were enrolled in a randomized, blinded, crossover experiment with a minimum 4‐week washout between treatments. Baseline corneal touch thresholds (CTT,
Lee S, Hector RC, Hess AM, Wotman KL.
europepmc   +2 more sources

Ropivacaine inhibits the malignant behavior of lung cancer cells by regulating retinoblastoma-binding protein 4 [PDF]

PeerJ, 2023
Background Ropivacaine is a local anesthetic commonly used in regional nerve blocks to manage perioperative pain during lung cancer surgery. Recently, the antitumor potential of ropivacaine has received considerable attention.
Weiai Jia, Junmei Shen, Sisi Wei, Chao Li, Jingpu Shi, Lianmei Zhao, Huiqun Jia   +6 more
doaj   +2 more sources

Subfascial infiltration of 0.5% ropivacaine, but not 0.25% ropivacaine, exacerbates damage and inflammation in surgically incised abdominal muscles of rats

Scientific Reports, 2022
Ropivacaine-induced myotoxicity in surgically incised muscles has not been fully investigated. We evaluated the effects of infiltration anesthesia with ropivacaine on damage, inflammation and regeneration in the incised muscles of rats undergoing ...
Dandan Shen, Yuki Sugiyama, Kumiko Ishida, Satoshi Fuseya, Takashi Ishida, Mikito Kawamata, Satoshi Tanaka   +6 more
doaj   +1 more source

Ropivacaine as the drug of choice for regional anesthesia: why so?

Медицина болю, 2021
While writing the article, we analyzed all the studies related to ropivacaine for the first half of 2021, which were published in PubMed. Previous review articles on ropivacaine were also analyzed.
Dmytro Dmytriiev, Yevhen Lisak
doaj   +1 more source

Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial

Pain Research and Management, 2022
TrialDesign. Patients undergoing laminoplasty and laminectomy often experience severe postoperative pain. Local infiltration analgesia during spine surgery significantly reduces postoperative pain, which only upholds for a short time.
Niti Shrestha, Bo Han, Xiying Wang, Wenqing Jia, Fang Luo   +4 more
doaj   +1 more source

Comparison of anaesthetic efficacy of ropivacaine (0.75% & 0.5%) with 2% lignocaine with adrenaline (1:200000) in surgical extraction of bilateral mandibular 3rd molars using IANB:a prospective, randomized, single blind study

Journal of Oral Biology and Craniofacial Research, 2021
Aim: To evaluate and compare the anaesthetic efficacy of 0.75% ropivacaine and 0.5% ropivacaine with 2% lignocaine with 1:200000 Adrenaline (LWA) for surgical extraction of bilateral mandibular 3rd molars using Direct inferior alveolar nerve block (IANB).
Kamil N. Rajpari, Neelam N. Andrade, Trupti Nikalje   +2 more
doaj   +1 more source

Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. [PDF]

PLoS ONE, 2017
Ropivacaine is a local anesthetic with similar potency but lower systemic toxicity than bupivacaine, the most commonly used spinal anesthetic. The present study concerns the development of a combined drug delivery system for ropivacaine, comprised of two
Camila Morais Gonçalves da Silva, Michelle Franz-Montan, Cíntia Elisabeth Gomez Limia, Lígia Nunes de Morais Ribeiro, Mário Antônio Braga, Viviane Aparecida Guilherme, Camila Batista da Silva, Bruna Renata Casadei, Cíntia Maria Saia Cereda, Eneida de Paula   +9 more
doaj   +1 more source

Effects of dexmedetomidine as an adjuvant to ropivacaine or ropivacaine alone on duration of postoperative analgesia: A systematic review and meta-analysis of randomized controlled trials.

PLoS ONE, 2023
BackgroundRopivacaine is a long-acting local anesthetic that is used to treat postoperative pain. Adjuvant use of dexmedetomidine in regional anesthesia may prolong the duration of analgesia.
Fangzhou Li, Liang Guo, Zijin Huang, Fei Lin, Linghui Pan   +4 more
doaj   +1 more source

Fast glycorrhachia and cerebrospinal fluid protein as predictors of sensory block in anesthesia with subarachnoid Ropivacaine [PDF]

, 2016
BACKGROUND: Identify if glycorrhachia and cerebrospinal fluid protein could influence the time of sensory block to T10, the duration and the metameric block's level, after a standard dose of Ropivacaine. METHODS: 80 patients, ASA I - III undergoing to
COLLINI, Saul, DE SIO, SIMONE, MERLIN, PAMELA, PACELLA, Elena, PACELLA, FERNANDA, Troisi, F   +5 more
core   +1 more source