A Method for Analysis of Free and Total Ropivacaine in Dog Plasma Using UHPLC-MS/MS. [PDF]
ABSTRACT Ropivacaine is a local anesthetic commonly used in veterinary anesthesia. A liquid chromatography–mass spectrometry (LC–MS) method was developed to quantify free and total ropivacaine in dog plasma, which included rapid equilibrium dialysis.
Verdier N, Hummel K, Razzazi-Fazeli E.
europepmc +2 more sources
Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. [PDF]
Ropivacaine is a local anesthetic with similar potency but lower systemic toxicity than bupivacaine, the most commonly used spinal anesthetic. The present study concerns the development of a combined drug delivery system for ropivacaine, comprised of two
Camila Morais Gonçalves da Silva +9 more
doaj +1 more source
The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity
Ropivacaine is a commonly used local anaesthetic, but its side effects remain largely unknown. In the present study, we investigated the side effects of ropivacaine in human neuronal SH-5Y5Y cells. We show that 0.5% and 1% ropivacaine could cause fission-
Yan Chen +3 more
doaj +1 more source
Fast glycorrhachia and cerebrospinal fluid protein as predictors of sensory block in anesthesia with subarachnoid Ropivacaine [PDF]
BACKGROUND: Identify if glycorrhachia and cerebrospinal fluid protein could influence the time of sensory block to T10, the duration and the metameric block's level, after a standard dose of Ropivacaine. METHODS: 80 patients, ASA I - III undergoing to
COLLINI, Saul +5 more
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BackgroundRopivacaine is a long-acting local anesthetic that is used to treat postoperative pain. Adjuvant use of dexmedetomidine in regional anesthesia may prolong the duration of analgesia.
Fangzhou Li +4 more
doaj +1 more source
BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga +4 more
doaj +1 more source
Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek +196 more
core +1 more source
Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood.
Pei-Lin Lin +5 more
doaj +1 more source
Analgesic effect of perineural magnesium sulphate for sciatic nerve block for diabetic toe amputation: A randomized trial. [PDF]
High concentrations of local anesthetics may be neurotoxic for diabetic patients. Additive perineural administration of magnesium was reported to decrease the consumption of local anesthetics for nerve block.
Jiehao Sun +6 more
doaj +1 more source
Ultrasound-Guided Femoral and Sciatic Nerve Blocks for Repair of Tibia and Fibula Fractures in a Bennett's Wallaby (Macropus rufogriseus) [PDF]
Locoregional anesthetic techniques may be a very useful tool for the anesthetic management of wallabies with injuries of the pelvic limbs and may help to prevent capture myopathies resulting from stress and systemic opioids’ administration.
Adami, C, Campoy, L, Monticelli, P
core +5 more sources

