Results 41 to 50 of about 27,133 (207)

Serum Concentration of Ropivacaine After Repeated Administration to Several Parts of the Head During Awake Craniotomy: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionDuring awake craniotomy, effective use of local anesthetics, such as ropivacaine, is critical. Blood concentrations of ropivacaine after repeated administration over a short period during awake craniotomy have not been studied.Materials and ...
Takehito Sato, Takahiro Ando, Ichiko Asano, Atsushi Mori, Kazuya Motomura, Kimitoshi Nishiwaki   +5 more
doaj   +1 more source

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

Frontiers in Medicine
ObjectiveThe efficacy of local anesthetics like ropivacaine in axillary brachial plexus blocks may be influenced by temperature, though its impact on the median effective concentration (EC50) remains unclear.
Alin Wang, Yunhao Shao, Yuling Zheng, Xiaoling Li, Bixin Huang, Ying Mai, Zhongqi Zhang   +6 more
doaj   +1 more source

Anesthetic efficacy and safety of ropivacaine 0.75% versus bupivacaine 0.5% for spinal anesthesia in patients undergoing lower limb orthopedic surgery

Asian Journal of Medical Sciences, 2023
Background: Ropivacaine, a new amino-amide local anesthetic agent, is similar in chemical structure to bupivacaine. The low solubility of ropivacaine leads to greater sensory-motor differentiation by blocking sensory nerve fiber more readily than motor ...
Pratiti J Gohil , Pankti Panchal , Gauri M. Panjabi , Jinal J. Gohil , Ushma H. Thakar , Raghav R. Rathi   +5 more
doaj   +1 more source

Comparison of caudal analgesia between ropivacaine and ropivacaine with clonidine in children: A randomized controlled trial

Saudi Journal of Anaesthesia, 2012
Background: Addition of clonidine to ropivacaine (0.2%) can potentially enhance analgesia without producing prolonged motor blockade. The aim of the present study was to compare the post-operative pain relieving quality of ropivacaine 0.2% and clonidine ...
Arpita Laha, Sarmila Ghosh, Haripada Das
doaj   +1 more source

The Median Effective Analgesic Concentration of Ropivacaine in Sciatic Nerve Block Guided by Ultrasound After Arthroscopic Anterior Cruciate Ligament Reconstruction: A Double-Blind Up-Down Concentration-Finding Study

Frontiers in Medicine, 2022
BackgroundThe median effective analgesic concentration (MEAC; EC50 = effective concentration in 50% patients) of ropivacaine in sciatic nerve block guided by ultrasound (US) required for effective postoperative analgesia following arthroscopic anterior ...
Cheng Xu, Fei Gu, Chengyu Wang, Yang Liu, Rui Chen, Quanhong Zhou, Jie Lu   +6 more
doaj   +1 more source

Ropivacaine withdrawal syndrome: a case report [PDF]

Revista Brasileira de Anestesiologia, 2020
Introduction and objectives: Ropivacaine is a long-acting local anesthetic that causes prolonged anesthesia and is beneficial for a wide variety of surgeries.
Dmitriy Viderman, Ivan Portnyagin, Philip la Fleur, Federico Bilotta   +3 more
doaj   +3 more sources

Controlled Release of Ropivacaine from Single-Armed (1-PCL) and Four-Armed PCL (4-PCL) Microspheres

International Journal of Polymer Science, 2019
Sustained release of anesthesia has shown great promise in the treatment of chronic pain in patients. In this research, we used neutralized ropivacaine as an anesthesia and poly(ε-caprolactone) (PCL) with different architectures to systematically study ...
Wei Xiong, Yue-kun Shen, Peng Dong, Ying Xiao, Xiong-qing Huang, Wen-qi Huang, Lu Yang, Xia Feng   +7 more
doaj   +1 more source

A comparative study of efficacy of ropivacaine (0.75%) with adjuvants – dexmedetomidine and fentanyl in supraclavicular brachial plexus block

Asian Journal of Medical Sciences, 2023
Background: Brachial plexus block is preferred to general anesthesia (GA) as it reduces many complications of GA, provides good intra and postoperative analgesia, adequate muscle relaxation.
Zaebha Shah Alam , Pradhan Monnaiah K , Sandeep S Kadam , Hema Viswanath K , Pedapolu Kishore Babu , Usha Rani S   +5 more
doaj   +1 more source

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

Comparable outcomes and early revision rates between restricted and unrestricted functional knee positioning in robotic‐assisted total knee arthroplasty for varus deformities ≥10°

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Functional knee positioning (FKPos) in total knee arthroplasty (TKA) optimises outcomes by balancing individual anatomical and soft tissue characteristics. Managing marked varus deformity presents challenges in achieving balance when tibial alignment is restricted to 3° of varus, necessitating either medial soft tissue release or ...
Christos Koutserimpas, Konstantinos Dretakis, Enejd Veizi, Nevzat Arıcan, Elvire Servien, Cécile Batailler, Sébastien Lustig   +6 more
wiley   +1 more source