Results 121 to 130 of about 1,746,350 (379)

VIPS: simple, efficient, and scalable cache coherence [PDF]

, 2016
Directory-based cache coherence is the de-facto standard for scalable shared-memory multi/many-cores and significant effort is invested in reducing its overhead.
Ros, Alberto
core   +1 more source

Literature-based discovery of diabetes- and ROS-related targets [PDF]

, 2010
Background Reactive oxygen species (ROS) are known mediators of cellular damage in multiple diseases including diabetic complications. Despite its importance, no comprehensive database is currently available for the genes associated with ROS.
A Erol, A Fontayne, A Iaccio, Adam D Schuyler, AG Reaume, AM Vincent, AM Vincent, AM Vincent, AM Vincent, American-Diabetes-Association, BJ Turner, C Figueroa-Romero, C Plake, D Rebholz-Schuhmann, David J States, E Schwedhelm, EH Sarsour, EL Feldman, EM Olofsson, Eva L Feldman, F Folli, FA Hakim, FR DeRubertis, H Ilieva, H V Jagadish, HB Lee, I Vastrik, J Hur, JL Edwards, JM Jimenez-Andrade, JS Pan, Junguk Hur, JW Russell, KA Sullivan, Kelli A Sullivan, KK Ohlemiller, L Hirschman, M Ashburner, M Brownlee, M Fukuda, M Fukuda, M Kanehisa, M Kawase, Manjusha Pande, N Kameyama, PJ Shaw, RA Fisher, S Cetinkalp, S Ghosh, T Matsunami, VI Perez, Y Aliciguzel, Y Benjamini, Yu Hong, Z Bagi   +54 more
core   +5 more sources

ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells

Oxidative Medicine and Cellular Longevity, 2019
Reactive oxygen species (ROS) are by-products of normal cell activity. They are produced in many cellular compartments and play a major role in signaling pathways.
A. Snezhkina, A. Kudryavtseva, O. Kardymon, M. Savvateeva, N. Melnikova, G. Krasnov, A. Dmitriev   +6 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Mitochondrial theory of skeletal muscle ageing –new facts, new doubts

Journal of Veterinary Research, 2019
For many years, scientists have been pursuing research on skeletal muscle ageing both in humans and animals. Studies on animal models have extended our knowledge of this mechanism in humans.
Słodki Sebastian, Bogucka Joanna
doaj   +1 more source

Cellular death, reactive oxygen species (ROS) and diabetic complications

Cell Death and Disease, 2018
Chronic or intermittent hyperglycemia is associated with the development of diabetic complications. Several signaling pathways can be altered by having hyperglycemia in different tissues, producing oxidative stress, the formation of advanced glycation ...
C. Volpe, Pedro Henrique Villar-Delfino, Paula Martins Ferreira dos Anjos, J. A. Nogueira-Machado   +3 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Surface Functionalization with Proanthocyanidins Provides an Anti-Oxidant Defense Mechanism That Improves the Long-Term Stability and Osteogenesis of Titanium Implants

International Journal of Nanomedicine, 2020
Jiahao Tang,1,2 Liang Chen,1,2 Deyi Yan,1,2 Zijian Shen,1,2 Bingzhang Wang,1,2 Sheji Weng,1,2 Zongyi Wu,1,2 Zhongjie Xie,1,2 Jiancan Shao,1,2 Lei Yang,1,2 Liyan Shen1,2 1The Second School of Medicine Wenzhou Medical University, Wenzhou, Zhejiang 325000 ...
Tang J, Chen L, Yan D, Shen Z, Wang B, Weng S, Wu Z, Xie Z, Shao J, Yang L, Shen L   +10 more
doaj  

Salidroside inhibits MAPK, NF-κB, and STAT3 pathways in psoriasis-associated oxidative stress via SIRT1 activation

Redox Report, 2019
Objectives: To unveil the role of SIRT1 in limiting oxidative stress in psoriasis and to further discuss the therapeutic prospects of salidroside in psoriasis.
Fengli Xu, Jixiang Xu, Xia Xiong, Yongqiong Deng   +3 more
doaj   +1 more source

ROS [PDF]

Current Biology, 2013
Glasauer, Andrea, Chandel, Navdeep S.
openaire   +2 more sources