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Murine Roseolovirus Induces Autoimmune Gastritis and Disrupts Thymic Antigen Presenting Cells.

The Journal of Immunology, 2021
Murine roseolovirus (MRV) is a beta-herpesvirus that is a natural murine pathogen and is genetically highly related to the human roseoloviruses, HHV6 and HHV7.
T. Bigley +5 more
semanticscholar +5 more sources

Comparison of methods for the detection of porcine cytomegalovirus/roseolovirus in relation to biosafety monitoring of xenotransplantation products

Xenotransplantation, 2023
The porcine cytomegalovirus, a porcine roseolovirus (PCMV/PRV), is widely distributed in pig populations. It has been shown that PCMV/PRV was transmitted by pig xenotransplants to non‐human primates, and significantly reduced the survival time of the ...
J. Denner +3 more
semanticscholar +4 more sources

Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical. [PDF]

Biochemistry and Cell Biology, 2017
U24 is a C-terminal membrane-anchored protein found in both human herpes virus type 6 and 7 (HHV-6 and HHV-7), with an N-terminal segment that is rich in prolines (PPxY motif in both HHV-6A and 7; PxxP motif in HHV-6A).
Yurou Sang +4 more
semanticscholar +5 more sources

Animal Models of Alzheimer’s Disease Should Be Controlled for Roseolovirus

Journal of Alzheimer's Disease, 2020
Animal models to study Alzheimer’s disease (AD) pathogenesis are under development. Since herpesviruses have been postulated to be capable of triggering the pathogenic process, AD animal models (mouse, pig, and non-human primates) should be controlled ...
J. Denner, R. Tanzi, S. Jacobson
semanticscholar +5 more sources

222: NEONATAL MURINE ROSEOLOVIRUS INFECTION DISRUPTS IMMUNE TOLERANCE AND INDUCES AUTOIMMUNE GASTRITIS