Results 81 to 90 of about 1,950 (144)

Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses

Ecology and Evolution, Volume 14, Issue 6, June 2024.
We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Anna R. Sjodin, Michael R. Willig, Armando Rodríguez‐Durán, Simon J. Anthony   +3 more
wiley   +1 more source

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Improving the safety of CAR‐T‐cell therapy: The risk and prevention of viral infection for patients with relapsed or refractory B‐cell lymphoma undergoing CAR‐T‐cell therapy

American Journal of Hematology, Volume 99, Issue 4, Page 662-678, April 2024.
Risk factors and prevention recommendations for viral infections in CAR T‐cell therapy. Abstract Chimeric antigen receptor (CAR) T‐cell therapy, an innovative immunotherapeutic against relapsed/refractory B‐cell lymphoma, faces challenges due to frequent viral infections.
Hu Qian, Xingcheng Yang, Tingting Zhang, Ping Zou, Yicheng Zhang, Weiwei Tian, Zekai Mao, Jia Wei   +7 more
wiley   +1 more source

Additional file 1 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 1: Supplementary Fig. 1. Peripheral, neonatal MRV infection in 5XFAD mice does not accelerate Aβ plaque burden. A, Schematic of experimental paradigm (6 mpi). B, C, Percent of CD4+ and CD8+ T cells in plasma 10 dpi (B) or 6 mpi (C). D, E, HJ3.4B+ immunostaining for Aβ plaque load in the cortex. F–I, Staining and quantification for Tau5+
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source

Identification of Novel Betaherpesviruses in Iberian Bats Reveals Parallel Evolution.

PLoS ONE, 2016
A thorough search for bat herpesviruses was carried out in oropharyngeal samples taken from most of the bat species present in the Iberian Peninsula from the Vespertilionidae, Miniopteridae, Molossidae and Rhinolophidae families, in addition to a colony ...
Francisco Pozo, Javier Juste, Sonia Vázquez-Morón, Carolina Aznar-López, Carlos Ibáñez, Inazio Garin, Joxerra Aihartza, Inmaculada Casas, Antonio Tenorio, Juan Emilio Echevarría   +9 more
doaj   +1 more source

Pesquisa de herpesvírus 6 em amostras de tecido cerebral de pacientes submetidos à cirurgia como tratamento para epilepsia [PDF]

, 2011
Human herpesvirus 6 (HHV-6) is a Betaherpesvirus associated with Roseola Infantum (Exanthema Subitum) in primary infection. Due to its neurotropic characteristic and latency in the central nervous system, many reports associate HHV-6 with epilepsy ...
Andreatta, Rafaela Manfro Rorato
core  

A Step‐by‐Step Guide for the Production of Recombinant Fluorescent TAT‐HA‐Tagged Proteins and their Transduction into Mammalian Cells

Current Protocols, Volume 4, Issue 3, March 2024.
Abstract Investigating the function of target proteins for functional prospection or therapeutic applications typically requires the production and purification of recombinant proteins. The fusion of these proteins with tag peptides and fluorescently derived proteins allows the monitoring of candidate proteins using SDS‐PAGE coupled with western ...
Christer Abou Anny, Sébastien Nouaille, Régis Fauré, Céline Schulz, Corentin Spriet, Isabelle Huvent, Christophe Biot, Tony Lefebvre   +7 more
wiley   +1 more source

Additional file 3 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 3: Supplementary Fig. 3. Effects of acute, intrahippocampal MRV infection on tau pathology. A, Schematic of experimental paradigm. B – G, Staining and quantification for Tau5+ total tau (B, C, D) and AT8+ phosphorylated tau in the cortex (E, F, G). p-tau: phosphorylated tau. Scale bar: 500 μm.
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source

High Torque teno virus load and outcome of patients undergoing allogeneic hematopoietic cell transplantation

Journal of Medical Virology, Volume 96, Issue 3, March 2024.
Abstract Quantification of Torque teno virus (TTV) load emerged as a marker of immunosuppression. Associations of TTV load with complications and survival after allogeneic hematopoietic cell transplantation (allo‐HCT) were controversial in published studies. In this prospective study, we aimed to identify factors influencing TTV load after allo‐HCT and
Micha Srour, Corentin Grenier, Leonardo Magro, Didier Hober, Ibrahim Yakoub‐Agha, Ilka Engelmann   +5 more
wiley   +1 more source

Additional file 2 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 2: Supplementary Fig. 2. Comparisons between MRV purified and unpurified stocks. A – C, Stocks were created from in vivo passage and collection of 7 day post neonatal infection thymi and were used directly (MRV Stock) or semi-purified (MRV Purified).
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source