Results 61 to 70 of about 1,342 (122)
, 2023 Additional file 1: Demonstration of real-time PCR testing of pig oocytes for PCMV/PRV. As positive control a gene block was used.
Hansen, Sabrina +7 more
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, 2022 Additional file 1: Supplementary Fig. 1. Peripheral, neonatal MRV infection in 5XFAD mice does not accelerate Aβ plaque burden. A, Schematic of experimental paradigm (6 mpi). B, C, Percent of CD4+ and CD8+ T cells in plasma 10 dpi (B) or 6 mpi (C). D, E, HJ3.4B+ immunostaining for Aβ plaque load in the cortex. F–I, Staining and quantification for Tau5+
Bigley, Tarin M. +12 more
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The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
wiley +1 more source
, 2022 Additional file 3: Supplementary Fig. 3. Effects of acute, intrahippocampal MRV infection on tau pathology. A, Schematic of experimental paradigm. B – G, Staining and quantification for Tau5+ total tau (B, C, D) and AT8+ phosphorylated tau in the cortex (E, F, G). p-tau: phosphorylated tau. Scale bar: 500 μm.
Bigley, Tarin M. +12 more
openaire +1 more source
Medicine Bulletin, Volume 1, Issue 1, Page 77-85, June 2025.Recent clinical trials transplanted gene‐edited pig hearts, kidneys, and a liver into eight human patients, demonstrating xenotransplantation's potential to address organ shortages. While showing promise, outcomes varied, highlighting key challenges including immune rejection and managing patient comorbidities, requiring further optimization.
Lisha Mou, Zuhui Pu, David K. C. Cooper
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Xenotransplantation, Volume 32, Issue 1, January/February 2025.ABSTRACT Porcine endogenous retroviruses (PERVs) are integrated into the genome of all pigs and can infect human cells in culture. However, no PERV infections have been reported in recipients following preclinical or clinical xenotransplantation or deliberate infection experiments.
Joachim Denner +4 more
wiley +1 more source
Working with Miraculous Mice: Mus musculus as a Model Organism
Current Protocols, Volume 4, Issue 10, October 2024.Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley +4 more
wiley +1 more source
Identification of Novel Betaherpesviruses in Iberian Bats Reveals Parallel Evolution.
PLoS ONE, 2016 A thorough search for bat herpesviruses was carried out in oropharyngeal samples taken from most of the bat species present in the Iberian Peninsula from the Vespertilionidae, Miniopteridae, Molossidae and Rhinolophidae families, in addition to a colony ...
Francisco Pozo +9 more
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Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses
Ecology and Evolution, Volume 14, Issue 6, June 2024.We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Anna R. Sjodin +3 more
wiley +1 more source
Журнал инфектологииClinical metagenomics methods significantly expand diagnostic capabilities, especially in cases where pathogens cannot be identified using traditional methods.
V. V. Gostev +12 more
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