Results 51 to 60 of about 1,342 (122)
Scientific Reports, 2022 Porcine cytomegalovirus (PCMV), that is actually a porcine roseolovirus (PRV), is a common herpesvirus in domestic pigs and wild boars. In xenotransplantation, PCMV/PRV has been shown to significantly reduce the survival time of pig kidneys and hearts in
S. Halecker +5 more
doaj +1 more source
Xenotransplantation, Volume 33, Issue 4, July/August 2026.ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Wayne J. Hawthorne +25 more
wiley +1 more source
Xenotransplantation Literature Update: January–June 2026
Xenotransplantation, Volume 33, Issue 4, July/August 2026.ABSTRACT In the first half of 2026, xenotransplantation advanced through refinement rather than dramatic new clinical milestones. Clinical studies described graft physiology, immune infiltration, complement activation, coagulation incompatibility, and early function in living recipients, decedent models, and clinical islet xenotransplantation ...
Kasra Shirini +3 more
wiley +1 more source
First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS).
PLoS ONE, 2023 Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Hina Jhelum +13 more
doaj +1 more source
Current Protocols, Volume 6, Issue 3, March 2026.Abstract The choice of cell source for generating induced pluripotent stem cells (iPSCs) is influenced by several factors, including accessibility, reprogramming efficiency, and the invasiveness of the cell collection procedure. Traditional sources such as skin fibroblasts or peripheral blood mononuclear cells often require invasive sampling, which can
Laurie Martineau +4 more
wiley +1 more source
Pig-to-human kidney xenotransplants using genetically modified minipigs
Cell Reports MedicineSummary: This study develops an observational model to assess kidney function recovery and xenogeneic immune responses in kidney xenotransplants, focusing on gene editing and immunosuppression.
Yi Wang +28 more
doaj +1 more source
Viruses, 2017 Tissue-culture adaptation of viruses can modulate infection. Laboratory passage and bacterial artificial chromosome (BAC)mid cloning of human cytomegalovirus, HCMV, resulted in genomic deletions and rearrangements altering genes encoding the virus entry ...
Joshua G. Tweedy +3 more
doaj +1 more source
Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders
Frontiers in Microbiology, 2018 Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty +11 more
doaj +1 more source
, 2022 Additional file 2: Supplementary Fig. 2. Comparisons between MRV purified and unpurified stocks. A – C, Stocks were created from in vivo passage and collection of 7 day post neonatal infection thymi and were used directly (MRV Stock) or semi-purified (MRV Purified).
Bigley, Tarin M. +12 more
openaire +1 more source
Humanized Mouse Models of Epstein Barr Virus Infection
Current Protocols, Volume 5, Issue 11, November 2025.Abstract The oncogenic Epstein Barr virus (EBV) is an exclusively human pathogen with related lymphocryptoviruses (γ1‐herpesviruses) only present in monkeys. Therefore, experimentation with EBV infection in a small animal model requires reconstitution or adoptive transfer of human lymphocyte populations, primarily EBV's main host cell, the human B cell.
Saskia Gertrud von Boxberg +5 more
wiley +1 more source