Results 71 to 80 of about 1,505 (144)
Potential Infectious Complications in Pig Xenograft Donors and Recipients
Transplant InternationalPreclinical and clinical xenotransplantation trials have shown that successful outcomes depend on a number of factors including the prevention of xenozoonoses.
Nicolas J. Mueller, Linda Scobie
doaj +1 more source
Xenotransplantation, Volume 32, Issue 1, January/February 2025.ABSTRACT Porcine endogenous retroviruses (PERVs) are integrated into the genome of all pigs and can infect human cells in culture. However, no PERV infections have been reported in recipients following preclinical or clinical xenotransplantation or deliberate infection experiments.
Joachim Denner +4 more
wiley +1 more source
Identification of Novel Betaherpesviruses in Iberian Bats Reveals Parallel Evolution.
PLoS ONE, 2016 A thorough search for bat herpesviruses was carried out in oropharyngeal samples taken from most of the bat species present in the Iberian Peninsula from the Vespertilionidae, Miniopteridae, Molossidae and Rhinolophidae families, in addition to a colony ...
Francisco Pozo +9 more
doaj +1 more source
Working with Miraculous Mice: Mus musculus as a Model Organism
Current Protocols, Volume 4, Issue 10, October 2024.Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley +4 more
wiley +1 more source
Russian Medical InquiryBackground: roseoloviruses, including human herpesvirus (HHV) 6A/B and HHV-7, are implicated in several diseases but remain underexplored among clinically healthy individuals. Aim: this study aims to assess the role of HHV-6A, HHV-6B, and HHV-7 in the onset of infectious and inflammatory diseases affecting the upper respiratory tract in children ...
P.V. Vlasov +6 more
openaire +1 more source
Detección de epitopes de la glicoproteína H del Herpesvirus Humano 6A. [PDF]
, 2018 Herpesviridae comprenden una gran familia de virus con ADN envuelta, todos emplean ortólogos de las mismas tres glicoproteínas, GB, gH y gL1. El género de Roseolovirus comprende el Herpesvirus humano 6 (HHV-6).
Pérez Ruiz, Joezer Jordán +1 more
core +1 more source
Журнал инфектологииClinical metagenomics methods significantly expand diagnostic capabilities, especially in cases where pathogens cannot be identified using traditional methods.
V. V. Gostev +12 more
doaj +1 more source
An Approach to Controlling Inflammation and Coagulation in Pig‐to‐Baboon Cardiac Xenotransplantation
Xenotransplantation, Volume 31, Issue 4, July/August 2024.ABSTRACT Introduction Inflammatory responses and coagulation disorders are a relevant challenge for successful cardiac xenotransplantation on its way to the clinic. To cope with this, an effective and clinically practicable anti‐inflammatory and anti‐coagulatory regimen is needed.
Martin Bender +30 more
wiley +1 more source
Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses
Ecology and Evolution, Volume 14, Issue 6, June 2024.We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Anna R. Sjodin +3 more
wiley +1 more source
Xenotransplantation, Volume 31, Issue 3, May/June 2024.Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley +1 more source