Results 41 to 50 of about 1,950 (144)

Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis

Вопросы вирусологии
Human herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva, Dmitry S. Tikhomirov, Mikhail Y. Drokov, Tatiana A. Tupoleva   +3 more
doaj   +3 more sources

Porcine Lymphotropic Herpesvirus (PLHV) Was Not Transmitted During Transplantation of Genetically Modified Pig Hearts into Baboons. [PDF]

Int J Mol Sci
Porcine lymphotropic herpesviruses -1, -2, and -3 (PLHV-1, PLHV-2, and PLHV-3) are gammaherpesviruses that are widespread in pigs. These viruses are closely related to the human pathogens Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus
Jhelum H, Bender M, Reichart B, Abicht JM, Längin M, Kaufer BB, Denner J.   +6 more
europepmc   +3 more sources

Detection of Herpesviruses (Predominantly HHV-6) in Patients with Guillain–Barré Syndrome [PDF]

Biomedicines
Background/Objectives: Guillain–Barré syndrome (GBS) is a neurological disease that affects the peripheral nerves. The exact cause of this condition is still uncertain, but cross-reactivity between pathogen antigens and nervous tissue may play a crucial ...
Jéssica Gonçalves Pereira, Tainá Madeira Barros Pontes, Fernanda Martins Maia Carvalho, André Borges Ferreira Gomes, Rafael Santos Erbisti, Ivanildo Pedro de Sousa Junior, Jeová Keny Baima Colares, Danielle Malta Lima, Vanessa Salete de Paula   +8 more
doaj   +2 more sources

OMICS Analyses in Xenotransplantation: Initial Findings, Key Precautions, and Virus Infections. [PDF]

Xenotransplantation
ABSTRACT OMICS analyses have the potential to greatly enhance our understanding of rejection and other processes in xenotransplantation. These approaches may therefore contribute to extending the survival time of xenotransplants. Initial OMICS studies in brain‐dead patients following transplantation of pig kidneys or hearts revealed increased ...
Denner J.
europepmc   +2 more sources

The landscape of viral associations in human cancers [PDF]

, 2020
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik, Borozan, Ivan, Brewer, Daniel S, Cooper, Colin S, Desai, Nikita, Eils, Roland, Ferretti, Vincent, Grundhoff, Adam, Iskar, Murat, Lichter, Peter, Moch, Holger, PCAWG Consortium, PCAWG Pathogens, Sültmann, Holger, Zapatka, Marc   +14 more
core   +8 more sources

Betaherpesvirus Incidence in Saliva Samples From Patients With Hematological Neoplasms: Frequency, Clinic and Diagnostic Insights. [PDF]

J Med Virol
ABSTRACT Hematological neoplasms (HN) are disorders originating in blood cells that hold significant epidemiological importance. Treatments available for these conditions can induce immunosuppression, and it increases the risk of viral infections and reactivations, mainly by Human betaherpesviruses (HCMV, HHV‐6, and HHV‐7).
Guimarães ACS, Gonçalves JP, Pereira NS, Bonfim FFO, Martinelli KG, Amarante MK, Yamada-Ogatta SF, Franco LC, Galhardi LCF, de Paula VS.   +9 more
europepmc   +2 more sources

Genomic Validation of PERV-C-Free Pigs to Support Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Porcine endogenous retroviruses (PERVs) are present in the germ lines of domesticated pigs (Sus scrofa) and related suids. There are three types of PERVs, PERV‐A, ‐B, and ‐C, which differ in their host range. PERV‐A and ‐B can infect human and porcine cells, while PERV‐C only infects porcine cells. PERV‐A and ‐B are found in the genomes of all
Benjamin NR, Madrigal G, Ishida Y, Catchen J, Allen KL, Pepin B, Roca AL.   +6 more
europepmc   +2 more sources

U24 from Roseolovirus interacts strongly with Nedd4 WW Domains [PDF]

Scientific Reports, 2017
AbstractU24 is a protein found in both roseoloviruses Human Herpes Virus type 6 and 7 (HHV-6 and HHV-7), with an N-terminus that is rich in prolines (PY motif in both HHV-6A and 7; PxxP motif in HHV-6A). Previous work has shown that the interaction between U24 and WW domains is important for endocytic recycling of T-cell receptors, but a cognate ligand
Yurou Sang, Rui Zhang, Walter R. P. Scott, A. Louise Creagh, Charles A. Haynes, Suzana K. Straus   +5 more
openaire   +2 more sources

Identification and Characterization of Two Novel Viruses in Ocular Infections in Reindeer [PDF]

, 2013
A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifer tarandus tarandus) in Norway during an outbreak
Bodewes, R. (Rogier), das Neves, C.G. (Carlos), Haagmans, B.L. (Bart), Kuiken, T. (Thijs), Leeuwen, M. (Marije) van, Osterhaus, A.D.M.E. (Albert), Schapendonk, C.M.E. (Claudia), Smits, S.L. (Saskia), Stalin Raj, V.S., Tryland, M. (Morten)   +9 more
core   +8 more sources

CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus Infection [PDF]

The Journal of Immunology, 2017
Abstract A recently described mouse homolog of the human roseoloviruses, murine roseolovirus (MRV), causes loss of peripheral and thymic CD4+ cells during neonatal infection of BALB/c mice. Despite significant disruptions to the normal adaptive immune response, infected BALB/c mice reproducibly recover from infection, consistent with ...
Swapneel J Patel, Wayne M Yokoyama
openaire   +2 more sources