Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis
Вопросы вирусологииHuman herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva +3 more
doaj +3 more sources
Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical
Biochemistry and Cell Biology, 2017 U24 is a C-terminal membrane-anchored protein found in both human herpes virus type 6 and 7 (HHV-6 and HHV-7), with an N-terminal segment that is rich in prolines (PPxY motif in both HHV-6A and 7; PxxP motif in HHV-6A). Previous work has shown that U24 interacts strongly with Nedd4 WW domains, in particular, hNedd4L-WW3*.
Yurou, Sang +4 more
openaire +4 more sources
Detection of Herpesviruses (Predominantly HHV-6) in Patients with Guillain–Barré Syndrome [PDF]
BiomedicinesBackground/Objectives: Guillain–Barré syndrome (GBS) is a neurological disease that affects the peripheral nerves. The exact cause of this condition is still uncertain, but cross-reactivity between pathogen antigens and nervous tissue may play a crucial ...
Jéssica Gonçalves Pereira +8 more
doaj +2 more sources
The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights [PDF]
BiomedicinesCardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation.
Martin Bender +23 more
doaj +2 more sources
Is There an Ethical Dilemma in Xenotransplantation? [PDF]
XenotransplantationABSTRACT As clinical trials in xenotransplantation commence, the question of whether participants may withdraw from research is being intensely debated. Some authors argue that xenotransplant recipients should be subject to lifelong monitoring because of the potential risk of zoonotic or xenozoonotic infections affecting third parties.
Denner J.
europepmc +2 more sources
Protein interactions of membrane protein U24 from Roseolovirus and implications for its function
, 2016 This dissertation describes the investigation of the interactions between the tail-anchored membrane protein U24 from Human Herpesvirus type 6A (HHV-6A) and type 7 (HHV-7) and its potential binding partners. The roles that these interactions play in U24s’ function will be presented.
Sang, Yurou
openaire +2 more sources
OMICS Analyses in Xenotransplantation: Initial Findings, Key Precautions, and Virus Infections. [PDF]
XenotransplantationABSTRACT OMICS analyses have the potential to greatly enhance our understanding of rejection and other processes in xenotransplantation. These approaches may therefore contribute to extending the survival time of xenotransplants. Initial OMICS studies in brain‐dead patients following transplantation of pig kidneys or hearts revealed increased ...
Denner J.
europepmc +2 more sources
Betaherpesvirus Incidence in Saliva Samples From Patients With Hematological Neoplasms: Frequency, Clinic and Diagnostic Insights. [PDF]
J Med VirolABSTRACT Hematological neoplasms (HN) are disorders originating in blood cells that hold significant epidemiological importance. Treatments available for these conditions can induce immunosuppression, and it increases the risk of viral infections and reactivations, mainly by Human betaherpesviruses (HCMV, HHV‐6, and HHV‐7).
Guimarães ACS +9 more
europepmc +2 more sources