Results 21 to 30 of about 1,342 (122)

The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights [PDF]

Biomedicines
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation.
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Maria Leuschen, Felicia Wall, Julia Radan, Elisabeth Neumann, Maren Mokelke, Ines Buttgereit, Sebastian Michel, Reinhard Ellgass, Katja Gieseke, Stig Steen, Audrius Paskevicius, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Martin B. Müller, Matthias Längin   +23 more
doaj   +2 more sources

Differences in DNA Binding Specificity among Roseolovirus Origin Binding Proteins

Virology, 2001
The Roseolovirus genus of the Betaherpesvirinae consists of the very closely related viruses, human herpesvirus 6 variants A and B (HHV-6A and HHV-6B) plus the somewhat more distantly related human herpesvirus 7 (HHV-7). The roseoloviruses each encode a homolog of the alphaherpesvirus origin binding protein (OBP) which is required for lytic DNA ...
Philip Pellett, Naoki Inoue, Laurie T Krug   +2 more
exaly   +3 more sources

Xenoperfusion-The Transformative Role of Machine Perfusion in Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Huwyler F, Stoerzer S, Clavien PA, Tibbitt MW.   +3 more
europepmc   +2 more sources

Genomic Validation of PERV-C-Free Pigs to Support Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Porcine endogenous retroviruses (PERVs) are present in the germ lines of domesticated pigs (Sus scrofa) and related suids. There are three types of PERVs, PERV‐A, ‐B, and ‐C, which differ in their host range. PERV‐A and ‐B can infect human and porcine cells, while PERV‐C only infects porcine cells. PERV‐A and ‐B are found in the genomes of all
Benjamin NR, Madrigal G, Ishida Y, Catchen J, Allen KL, Pepin B, Roca AL.   +6 more
europepmc   +2 more sources

An Approach to Controlling Inflammation and Coagulation in Pig-to-Baboon Cardiac Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Introduction Inflammatory responses and coagulation disorders are a relevant challenge for successful cardiac xenotransplantation on its way to the clinic. To cope with this, an effective and clinically practicable anti‐inflammatory and anti‐coagulatory regimen is needed.
Bender M, Reichart B, Figueiredo C, Burgmann JM, Leuschen M, Wall F, Radan J, Neumann E, Mokelke M, Buttgereit I, Michel S, Ellgass R, Egerer S, Lange A, Baehr A, Kessler B, Kemter E, Klymiuk N, Denner J, Godehardt AW, Tönjes RR, Hagl C, Gebauer M, Binder U, Skerra A, Ayares D, Wolf E, Schmoeckel M, Brenner P, Längin M, Abicht JM.   +30 more
europepmc   +2 more sources

Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis

Вопросы вирусологии
Human herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva, Dmitry S. Tikhomirov, Mikhail Y. Drokov, Tatiana A. Tupoleva   +3 more
doaj   +3 more sources

Potential Infectious Complications in Pig Xenograft Donors and Recipients [PDF]

Transplant International
Preclinical and clinical xenotransplantation trials have shown that successful outcomes depend on a number of factors including the prevention of xenozoonoses.
Nicolas J. Mueller, Linda Scobie
doaj   +2 more sources

Detection of Herpesviruses (Predominantly HHV-6) in Patients with Guillain–Barré Syndrome [PDF]

Biomedicines
Background/Objectives: Guillain–Barré syndrome (GBS) is a neurological disease that affects the peripheral nerves. The exact cause of this condition is still uncertain, but cross-reactivity between pathogen antigens and nervous tissue may play a crucial ...
Jéssica Gonçalves Pereira, Tainá Madeira Barros Pontes, Fernanda Martins Maia Carvalho, André Borges Ferreira Gomes, Rafael Santos Erbisti, Ivanildo Pedro de Sousa Junior, Jeová Keny Baima Colares, Danielle Malta Lima, Vanessa Salete de Paula   +8 more
doaj   +2 more sources

Murine Roseolovirus, Historically Known as Murine Thymic Lymphotropic Virus [PDF]

Journal of Virology, 2017
Chuanwu Wang
exaly   +3 more sources

Roseolovirus DNA in the Colonic Mucosa of HIV‐Seropositive Patients with Diarrhea [PDF]

Clinical Infectious Diseases, 2003
Henri Agut, Agut Henri, Beaugerie Laurent   +2 more
exaly   +2 more sources