Potential Infectious Complications in Pig Xenograft Donors and Recipients [PDF]
Transplant InternationalPreclinical and clinical xenotransplantation trials have shown that successful outcomes depend on a number of factors including the prevention of xenozoonoses.
Nicolas J. Mueller, Linda Scobie
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Presence of porcine cytomegalovirus, a porcine roseolovirus, in wild boars in Italy and Germany. [PDF]
Arch Virol, 2023 Abstract Porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV) that is closely related to human herpesviruses 6 and 7, is commonly found in commercial pigs. PCMV/PRV is important in xenotransplantation, because in preclinical trials in which pig organs were transplanted into non-human primates, transmission of PCMV/PRV was ...
Hansen S +6 more
europepmc +5 more sources
Role of a Porcine Herpesvirus, PCMV/PRV, in Xenotransplantation [PDF]
Transplant InternationalXenotransplantation using pig organs may be associated with the transmission of porcine viruses that could cause disease in recipients. A well-known example is the porcine cytomegalovirus, which is actually a porcine roseolovirus, hence abbreviated as ...
Joachim Denner
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Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7 [PDF]
Frontiers in Immunology, 2022 Grant C. Weaver +7 more
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CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus Infection [PDF]
The Journal of Immunology, 2017 Abstract A recently described mouse homolog of the human roseoloviruses, murine roseolovirus (MRV), causes loss of peripheral and thymic CD4+ cells during neonatal infection of BALB/c mice. Despite significant disruptions to the normal adaptive immune response, infected BALB/c mice reproducibly recover from infection, consistent with ...
Swapneel J Patel, Wayne M Yokoyama
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Roseolovirus-associated encephalitis in immunocompetent and immunocompromised individuals [PDF]
Journal of NeuroVirology, 2016 The roseoloviruses, human herpesvirus (HHV)-6A, HHV-6B, and HHV-7, can cause severe encephalitis or encephalopathy. In immunocompetent children, primary HHV-6B infection is occasionally accompanied by diverse clinical forms of encephalitis. Roseolovirus coinfections with heterologous viruses and delayed primary HHV-7 infection in immunocompetent adults
Ongrádi, Joseph +4 more
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Possible Relation of Roseolovirus Infection with Fibromyalgia / Iespējamā Roseolovīrusu Infekcijas Saistība Ar Fibromialīiju [PDF]
Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences., 2016 Abstract Fibromyalgia (FM) is a chronic widespread pain disorder that impacts 0.5%-7% of the general population worldwide. The aetiology and pathogenesis of the disease are still unknown. Human herpesvirus-6 and -7 belong to the family Herpesviridae, subfamily Betaherpesvirinae, and genus Roseolovirus and are immunomodulating viruses ...
Svetlana Čapenko +6 more
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Detection of human herpesvirus 6 and 7 DNA in saliva from healthy adults from Rio de Janeiro, Brazil [PDF]
Memorias do Instituto Oswaldo Cruz, 2010 In this study, we aimed to evaluate virus shedding in the saliva of healthy adults from the metropolitan region of the city of Rio de Janeiro, Brazil, in order to verify the prevalence of both human herpesviruses 6 and 7 (HHV-6, HHV-7). The studied group
Ivna M Magalhães +7 more
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, 2019 The study of herpesviruses has been fruitful, not only revealing mechanisms that drive disease, but also providing insight into diverse processes including oncogenesis and immune regulation .
Patel, Swapneel
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Mouse Models for Human Herpesviruses
Pathogens, 2023 More than one hundred herpesviruses have been isolated from different species so far, with nine infecting humans. Infections with herpesviruses are characterized by life-long latency and represent a significant challenge for human health.
Ivana Kutle, Anne Dittrich, Dagmar Wirth
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