Results 31 to 40 of about 1,435 (139)

Differential Impacts of HHV-6A versus HHV-6B Infection in Differentiated Human Neural Stem Cells

Frontiers in Immunology, 2022
Within the family Herpesviridae, sub-family β-herpesvirinae, and genus Roseolovirus, there are only three human herpesviruses that have been described: HHV-6A, HHV-6B, and HHV-7.
Elham Bahramian, Elham Bahramian, Mercede Furr, Jerry T. Wu, Ruben Michael Ceballos, Ruben Michael Ceballos, Ruben Michael Ceballos, Ruben Michael Ceballos   +7 more
doaj   +1 more source

U24 from Roseolovirus interacts strongly with Nedd4 WW Domains [PDF]

Scientific Reports, 2017
AbstractU24 is a protein found in both roseoloviruses Human Herpes Virus type 6 and 7 (HHV-6 and HHV-7), with an N-terminus that is rich in prolines (PY motif in both HHV-6A and 7; PxxP motif in HHV-6A). Previous work has shown that the interaction between U24 and WW domains is important for endocytic recycling of T-cell receptors, but a cognate ligand
Yurou Sang, Rui Zhang, Walter R. P. Scott, A. Louise Creagh, Charles A. Haynes, Suzana K. Straus   +5 more
openaire   +2 more sources

Longitudinal study on oral shedding of human betaherpesviruses 6 and 7 in renal transplant recipients reveals active replication

Journal of Oral Microbiology, 2020
Backgroung Roseolovirus latency and persistence in salivary glands that are frequently reactivated after renal transplantation to cause infection have been reported.
Jéssica Vasques Raposo, Dmitry José De Santana Sarmento, Rafaela Barbosa Da Silva Pinto, Amanda Oliveira Lopes, Marina Gallottini, Tânia Regina Tozetto-Mendoza, Paulo Henrique Braz-Silva, Vanessa Salete de Paula   +7 more
doaj   +1 more source

Xenoperfusion-The Transformative Role of Machine Perfusion in Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Huwyler F, Stoerzer S, Clavien PA, Tibbitt MW.   +3 more
europepmc   +2 more sources

β-Herpesviruses in Febrile Children with Cancer

Emerging Infectious Diseases, 2008
We conducted a cross-sectional study of β-herpesviruses in febrile pediatric oncology patients (n = 30), with a reference group of febrile pediatric solid-organ transplant recipients (n = 9).
Stephanie Yee-Guardino, Kate Gowans, Belinda Yen-Lieberman, Pamela Berk, Debra Kohn, Fu-Zhang Wang, Lara Danziger-Isakov, Camille Sabella, Sarah Worley, Philip E. Pellett, Johanna Goldfarb   +10 more
doaj   +1 more source

Genomic Validation of PERV-C-Free Pigs to Support Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Porcine endogenous retroviruses (PERVs) are present in the germ lines of domesticated pigs (Sus scrofa) and related suids. There are three types of PERVs, PERV‐A, ‐B, and ‐C, which differ in their host range. PERV‐A and ‐B can infect human and porcine cells, while PERV‐C only infects porcine cells. PERV‐A and ‐B are found in the genomes of all
Benjamin NR, Madrigal G, Ishida Y, Catchen J, Allen KL, Pepin B, Roca AL.   +6 more
europepmc   +2 more sources

Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation

Viruses, 2021
Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases
Joachim Denner
doaj   +1 more source

General and Ophthalmic Manifestations of Herpes Virus Infections

Oftalʹmologiâ, 2016
Herpes viruses are a large group of DNA viruses causing a wide variety of diseases in humans. The exponential growth of medicine in general and advanced achievements of virology in particular authentically verified a wide spectrum of diseases in humans ...
S. V. Sdobnikova, N. A. Тroitskaya, Z. V. Surnina, L. S. Pateyuk   +3 more
doaj   +1 more source

Studying the Interactions of U24 from HHV-6 in Order to Further Elucidate Its Potential Role in MS

Viruses, 2022
A number of studies have suggested that human herpesvirus 6A (HHV-6A) may play a role in multiple sclerosis (MS). Three possible hypotheses have been investigated: (1) U24 from HHV-6A (U24-6A) mimics myelin basic protein (MBP) through analogous ...
Keng-Shuo Pi, Daria Bortolotti, Yurou Sang, Giovanna Schiuma, Silvia Beltrami, Sabrina Rizzo, Alessandra Bortoluzzi, Eleonora Baldi, A. Louise Creagh, Charles A. Haynes, Roberta Rizzo, Suzana K. Straus   +11 more
doaj   +1 more source

An Approach to Controlling Inflammation and Coagulation in Pig-to-Baboon Cardiac Xenotransplantation. [PDF]

Xenotransplantation
ABSTRACT Introduction Inflammatory responses and coagulation disorders are a relevant challenge for successful cardiac xenotransplantation on its way to the clinic. To cope with this, an effective and clinically practicable anti‐inflammatory and anti‐coagulatory regimen is needed.
Bender M, Reichart B, Figueiredo C, Burgmann JM, Leuschen M, Wall F, Radan J, Neumann E, Mokelke M, Buttgereit I, Michel S, Ellgass R, Egerer S, Lange A, Baehr A, Kessler B, Kemter E, Klymiuk N, Denner J, Godehardt AW, Tönjes RR, Hagl C, Gebauer M, Binder U, Skerra A, Ayares D, Wolf E, Schmoeckel M, Brenner P, Längin M, Abicht JM.   +30 more
europepmc   +2 more sources