Results 141 to 150 of about 16,425 (239)

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

open access: yesThe FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti   +8 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

Vol. XV, Tab 52 - Rosetta Stone\u27s Reply Brief in Support of its Motion for Partial Summary Judgment as to Liability [PDF]

open access: yes, 2010
Exhibits from the un-sealed joint appendix for Rosetta Stone Ltd., v. Google Inc., No. 10-2007, on appeal to the 4th Circuit. Issue presented: Under the Lanham Act, does the use of trademarked terms in keyword advertising result in infringement when ...
Rosetta Stone
core  

Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization

open access: yesThe FEBS Journal, EarlyView.
PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe   +6 more
wiley   +1 more source

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

open access: yesThe FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo   +6 more
wiley   +1 more source

A comprehensive study on ferredoxin isoforms in the cyanobacterium Synechocystis sp. PCC 6803

open access: yesThe FEBS Journal, EarlyView.
Ferredoxins are small FeS cluster‐containing proteins that play a central role in distributing electrons within the cell. The cyanobacterium Synechocystis sp. PCC 6803 contains several ferredoxin isoforms and their biophysical properties (UV/Vis and EPR spectra, Em potential), expression patterns, and interactions with the electron donors photosystem I
Marko Boehm   +14 more
wiley   +1 more source

Toward a minimal amino acid alphabet for protein design

open access: yesThe FEBS Journal, EarlyView.
Proteins are built from 20 canonical amino acids; however, it is interesting to investigate whether they can also be formed from reduced amino acid alphabets. Using protein design, we designed proteins based on all alphabets comprising 2 to 10 ‘early’ amino acids (those likely to have been present before the origin of life).
Karel Půbal   +5 more
wiley   +1 more source

Enhancing Recharge Beneath Low‐Permeability Landscapes with Small‐Diameter Drywells: Token Creek, WI

open access: yesGroundwater, EarlyView.
Shallow, small‐diameter drywells provide enhanced recharge in rural landscapes, bypassing the low infiltration rates caused by low permeability surficial soils and high ET rates. One year of monitoring data show several recharge events and overall high water quality.
Samantha C. Kershner   +2 more
wiley   +1 more source

Translating coexistence: Inside Japan's public multilingualism

open access: yesJapanese Journal of Sociology, Volume 34, Issue 1, Page 152-170, March 2025.
Abstract Provision of translated material for both international residents and tourists is a key part of the work of public offices around Japan. The way in which this translation is viewed and carried out, and its relationship to dominant modes of conceptualizing multiculturalism, has not received much attention in the literature.
Gregory Friedman
wiley   +1 more source

PtoHY5 integrates photoperiodic signals with the ABA pathway to coordinate growth cessation and dormancy in Populus

open access: yesJournal of Integrative Plant Biology, EarlyView.
In Populus, short days deactivate the growth‐promoting protein PtoHY5, turning off a growth accelerator and activating an abscisic acid‐driven brake. This directly couples growth cessation with dormancy, underscoring the role of abscisic acid in synchronizing these transitions for winter survival.
Hongbin Wei   +9 more
wiley   +1 more source

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