Results 151 to 160 of about 42,471 (305)

Improving Protein Structure Prediction Using Integrative Cryo-EM and Ion Mobility Mass Spectrometry Modeling. [PDF]

J Chem Theory Comput
Howard JB, Narayanasamy A, Lindert S.
europepmc   +1 more source

Commentary: Reframing Massive Carbon Input During the PETM and a Grand 66 Million Year Geoscience Puzzle

Geophysical Research Letters, Volume 53, Issue 12, 28 June 2026.
Abstract Despite decades of research, hundreds of peer‐reviewed papers, and considerable relevance to Earth's future, the rapid global warming and tremendous CO2 input at the start of the Paleocene‐Eocene Thermal Maximum (PETM) remain highly debated.
Gerald R. Dickens
wiley   +1 more source

Using experimental results of protein design to guide biomolecular energy-function development. [PDF]

PLoS Comput Biol
Haddox HK, Rocklin GJ, Motta FC, Strickland D, Halabiya SF, Cordray C, Park H, Klavins E, Baker D, DiMaio F.   +9 more
europepmc   +1 more source

Expression of translation elongation factor P in Kocuria rhizophila is regulated by an inducible weak promoter. [PDF]

BMC Microbiol
Li C, Zhang X, Peng X, Ni H, Zou L, Toda H, Long Z.   +6 more
europepmc   +1 more source

Sesto Truttedio Clemente in una nuova iscrizione da Fano

, 1986
PICU
BERNARDELLI, ROSETTA
core  

Semi‐Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Semi‐rational engineering yields a thermostable Bacillus simplex formate dehydrogenase variant (Q125F) with a 25‐fold longer half‐life at 60°C and strong resistance to chemo‐inactivation. Molecular dynamics reveal enhanced π–π interactions stabilizing a flexible loop and enabling efficient NADH regeneration for robust biocatalytic detoxification ...
Rattima Boonkumkrong, Sahachat Soithongcharoen, Pitchayathida Mee‐udorn, Paweenapon Chunthaboon, Somchart Maenpuen, Thanyada Rungrotmongkol, Pratchaya Watthaisong, Ruchanok Tinikul   +7 more
wiley   +1 more source

CLIMBS: Assessing Carbohydrate-Protein Interactions through a Graph Neural Network Classifier Using Synthetic Negative Data. [PDF]

J Chem Inf Model
Luo Y, Parmeggiani F.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, Volume 16, Issue 6, Page 1087-1101, June 2026.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Rosetta

Interdisciplinary Studies in Literature and Environment, 2014
openaire   +2 more sources

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source