Results 171 to 180 of about 42,471 (305)

Rosetta Armstead court transcript

Hamilton County Court of Common Pleas transcript in the 1855 case of Rosetta Armstead (sometimes written Armistead), a sixteen year old slave who was brought to Ohio by an agent of her master. As Ohio was a free state, Rosetta sued for her freedom in the

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Impact of Process Interruptions in the Production of Lysates for Cell‐Free Expression Systems

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1615-1623, June 2026.
ABSTRACT Cell‐free gene expression systems offer cell‐like functionalities outside the confines of the cell, garnering increasing interest for applications from biomanufacturing to sensing. As applications expand, the need to implement economically scaled processes to produce cellular lysates grows.
Katherine A. Rhea, Ethan N. Walters, Julie L. Zacharko, Mia J. Seergae, Thomas R. Laws, Thomas C. Maishman, Yun‐Nam Choi, John T. Lazar, Ashty Karim, Weston Kightlinger, Michael C. Jewett, Matthew W. Lux   +11 more
wiley   +1 more source

VUStruct: A compute pipeline for high throughput and personalized structural biology. [PDF]

PLoS Comput Biol
Moth CW, Sheehan JH, Al Mamun A, Sivley RM, Gulsevin A, Rinker DC, Mchaourab ZF, Undiagnosed Diseases Network, Capra JA, Meiler J.   +9 more
europepmc   +1 more source

Enzymatic Synthesis of NAD+

Current Protocols, Volume 6, Issue 6, June 2026.
Abstract Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite involved in numerous biological processes, functioning both as a redox cofactor in cellular energy metabolism and as a co‐substrate for NAD+‐utilizing enzymes, including sirtuins and poly(ADP‐ribose) polymerases.
Emily Boyle, Olivia Zhang, Yana Cen
wiley   +1 more source

Computational design of generalist cyclopropanases with stereodivergent selectivity. [PDF]

Nat Commun
Shen Z, Siriboe MG, Ren X, Dayananda T, Jenkins JL, Khare SD, Fasan R.   +6 more
europepmc   +1 more source

Artificial intelligence in the assessment of epilepsy‐related genetic mutations: Learned from GABAA receptors and GABA transporter 1

Epilepsia Open, Volume 11, Issue 3, Page 740-751, June 2026.
Abstract This review examines how recent genetic and technological advances have transformed our understanding and treatment of genetic epilepsies (GEs), with a focus on disorders involving GABAA receptors (GABRs) and the GABA transporter 1 (GAT‐1) encoded by SLC6A1.
Juexin Wang, Jing‐Qiong Kang
wiley   +1 more source

Development of Antagonist Peptides of the Crk/CrkL SH2 Domains by Modifying the Peripheral Amino Acid Residues of the YXXP Motif. [PDF]

Biochemistry
Park T, Roy A, Douglas JT, Harned L, Neuenswander SA, Large N, Mudduluru G, Broward M, Johnson DK.   +8 more
europepmc   +1 more source

Single‐Sequence Deep Learning Delivers Crystal‐Quality Models of Covalent K‐Ras G12 Hotspot Complexes

IUBMB Life, Volume 78, Issue 6, June 2026.
ABSTRACT Structure‐based design of covalent drugs has achieved tremendous success by understanding and leveraging the three‐dimensional interactions between small‐molecule drug candidates and their protein targets. However, this approach traditionally relies on high‐resolution co‐complex structures obtained by X‐ray crystallography, NMR, or cryo‐EM ...
Sungwon Jung, Qinheng Zheng, Kevan M. Shokat   +2 more
wiley   +1 more source

Molecular characterization of Eimeria necatrix surface antigen SAG8 and SAG36 genes and their immunoprotective efficacy in chicken. [PDF]

BMC Vet Res
Wang F, Zhang C, Feng Y, Yan D, Liu D, Su S, Hou Z, Xu J, Tao J.   +8 more
europepmc   +1 more source

Absolute Quantification of Brain Deuterium Metabolic Imaging in Healthy Volunteers and Glioblastoma Patients at 7T

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3077-3094, June 2026.
ABSTRACT Purpose We present a method for absolute quantification of deuterated metabolites in vivo at 7T. We describe acquisition protocols and an analysis pipeline compatible with 7T Terra MRIs. We apply them using a 2H/1H receive array in healthy volunteers and glioblastoma patients.
Jabrane Karkouri, Masha Novoselova, Sarah Miller, Minghao Zhang, Alexandra Constantinou, Carina Graf, Özlem Ipek, Daniel Atkinson, Brandon Tramm, Scott Schillak, Richard Mair, Kevin Brindle, Christopher T. Rodgers   +12 more
wiley   +1 more source