Results 151 to 160 of about 90,351 (277)

Outcomes following intradetrusor onabotulinumtoxinA injections and sacral neuromodulation in older men

open access: yesBJUI Compass, Volume 7, Issue 4, April 2026.
Abstract Objectives This study aims understand the outcomes following intradetrusor onabotulinumtoxinA injections and sacral neuromodulation (SNM) in a national cohort of male Medicare beneficiaries with overactive bladder (OAB) Subjects and Methods This is a retrospective cohort study of a 100% sample of fee‐for‐service male Medicare beneficiaries ...
Leo D. Dreyfuss   +6 more
wiley   +1 more source

Computational design of generalist cyclopropanases with stereodivergent selectivity. [PDF]

open access: yesNat Commun
Shen Z   +6 more
europepmc   +1 more source

Recombinant Amelogenin as a Potential Alternative to Enamel Matrix Derivatives in Periodontal Regeneration: A Scoping Review of Its Biological Activity, Synthesis and Delivery Systems

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objective The objective of this review is to evaluate the existing literature on the regenerative potential of recombinant amelogenin, with a particular emphasis on the biological activity, synthesis, and delivery systems relevant to periodontal regeneration.
Jie Dan Denny Luo   +4 more
wiley   +1 more source

Method Development for the Analysis of Carbonaceous Chondrites by Laser Desorption/Ionization and Secondary Ion Time‐of‐Flight Mass Spectrometry

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 4, April 2026.
ABSTRACT This study focuses on the development of a laser desorption/ionization mass spectrometric method for analyzing carbonaceous chondrites, meteorites that may hold clues to the origin of life. Since carbonaceous chondrites are only available in small quantities, we initially designed an artificial meteorite material (the mineral forsterite) doped
Edita Rados   +2 more
wiley   +1 more source

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao   +6 more
wiley   +1 more source

Structural and evolutionary dissection of NADPH‐binding motifs in NADPH‐preferring ene‐reductases

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Ene‐reductases (ERs) catalyze nicotinamide‐dependent, stereoselective reductions of activated CC bonds. While their catalytic chemistry and applications are well‐explored, cosubstrate (NAD(P)H) binding remains poorly understood. Most ERs strongly prefer NADPH despite lacking canonical dinucleotide‐binding folds and instead employ flexible ...
Bianca Kerschbaumer   +7 more
wiley   +1 more source

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