The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging [PDF]
Frontiers in Cellular Neuroscience, 2013 The subventricular zone (SVZ) is the largest source of newly generated cells in the adult mammalian brain. SVZ-derived neuroblasts migrate via the rostral migratory stream (RMS) to the olfactory bulb (OB), where they differentiate into mature neurons ...
Vivian eCapilla-Gonzalez +4 more
doaj +9 more sources
A tissue-engineered rostral migratory stream for directed neuronal replacement [PDF]
Neural Regeneration Research, 2018 New neurons are integrated into the circuitry of the olfactory bulb throughout the lifespan in the mammalian brain—including in humans. These new neurons are born in the subventricular zone and subsequently mature as they are guided over long distances ...
John C O'Donnell +3 more
doaj +4 more sources
EGF-induced expansion of migratory cells in the rostral migratory stream. [PDF]
PLoS ONE, 2012 The presence of neural stem cells in the adult brain is currently widely accepted and efforts are made to harness the regenerative potential of these cells. The dentate gyrus of the hippocampal formation, and the subventricular zone (SVZ) of the anterior
Olle R Lindberg +4 more
doaj +4 more sources
Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream. [PDF]
PLoS Pathogens, 2016 It is poorly understood how progressive brain swelling in experimental cerebral malaria (ECM) evolves in space and over time, and whether mechanisms of inflammation or microvascular sequestration/obstruction dominate the underlying pathophysiology.
Angelika Hoffmann +10 more
doaj +7 more sources
Astrocyte Transcriptomics in a Three-Dimensional Tissue-Engineered Rostral Migratory Stream [PDF]
CellsThe glial tube is a longitudinal structure predominantly composed of densely bundled, aligned astrocytes that projects from the subventricular zone (SVZ) to the olfactory bulb. Neural precursor cells (NPCs) generated in the SVZ migrate through this glial
Michael R. Grovola +5 more
doaj +3 more sources
Identification of the rostral migratory stream in the canine and feline brain. [PDF]
PLoS ONE, 2012 In the adult rodent brain, neural progenitor cells migrate from the subventricular zone of the lateral ventricle towards the olfactory bulb in a track known as the rostral migratory stream (RMS).
Saafan Z Malik +6 more
doaj +5 more sources
Neuronal precursor cells with dopaminergic commitment in the rostral migratory stream of the mouse. [PDF]
Sci Rep, 2019 Neuroblasts born in the subventricular zone of adult mammals migrate via the rostral migratory stream into the granular cell layer or periglomerular layer of the olfactory bulb to differentiate into interneurons. To analyze if new neurons in the granular
Schweyer K +5 more
europepmc +9 more sources
An implantable human stem cell-derived tissue-engineered rostral migratory stream for directed neuronal replacement [PDF]
Communications Biology, 2021 O’Donnell et al. describe their Tissue-Engineered Rostral Migratory Stream (TE-RMS) comprised of human astrocyte-like cells that can be derived from adult gingival stem cells within one week, which reorganizes into bundles of bidirectional ...
John C. O’Donnell +6 more
doaj +2 more sources
Neural Regeneration Research, 2020 The binding properties of neural cell adhesion molecule are modulated by a polysialic acid moiety. This plays an important role in the migration of adult born neuroblasts from their area of origin, the subventricular zone, towards the olfactory bulb ...
Jannis Gundelach, Michael Koch
doaj +2 more sources
A three-dimensional tissue-engineered rostral migratory stream as an in vitro platform for subventricular zone-derived cell migration [PDF]
Frontiers in Bioengineering and BiotechnologyIn the brains of most adult mammals, neural precursor cells (NPCs) from the subventricular zone (SVZ) migrate through the rostral migratory stream (RMS) to replace olfactory bulb interneurons.
Erin M. Purvis +12 more
doaj +2 more sources