FMRP regulates postnatal neuronal migration via MAP1B
eLifeThe fragile X syndrome (FXS) represents the most prevalent form of inherited intellectual disability and is the first monogenic cause of autism spectrum disorder.
Salima Messaoudi +8 more
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Magnetic resonance imaging of migrating neuronal precursors in normal and hypoxic-ischemic neonatal rat brains by intraventricular MPIO labeling [PDF]
, 2008 Proceedings of the IEEE Engineering in Medicine and Biology Society Conference, 2008, p. 363-366In this study, 10-day-old normal rats (n=6) and hypoxic-ischemic (H-I) neonatal rats (n=6) were injected with the micronsized iron oxide particles (MPIOs ...
Liu, J, Liu, Y, Niu, G, Wu, EX, Yang, J
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Neurobiology of Disease, 2009 The neuropeptide Y (NPY) is widely expressed in the central nervous system and has been shown to stimulate neurogenesis in the hippocampus and the olfactory epithelium.
Mickaël Decressac +5 more
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Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone
Cell Reports, 2018 Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent neural stem cells (NSCs). V-SVZ NSCs are a reservoir for new olfactory bulb (OB) neurons that migrate through the rostral migratory stream (RMS ...
Anna Engler +11 more
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MRI detection of progenitor cell migrations during postnatal rat brain development by in situ MPIO labeling [PDF]
, 2009 Molecules & Cells: Novel Applications - Poster presentationIn this study, micron-sized iron oxide particles (MPIOs) were injected into the left anterior lateral ventricle of 10-day-old normal rats.
Liu, J +6 more
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Significance of the dynamic expression of Pax6 and Dlx2 in the postnatal periventricular zone cells
Frontiers in Cellular Neuroscience, 2012 Bhaskar eSaha
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Olfactory bulb anomalies in KBG syndrome mouse model and patients
BMC MedicineANKRD11 (ankyrin repeat domain 11) is a chromatin regulator and the only gene associated with KBG syndrome, a rare neurodevelopmental disorder. We have previously shown that Ankrd11 regulates murine embryonic cortical neurogenesis.
Kara Goodkey +11 more
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Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain [PDF]
, 1886 Precursor cells found in the subventricular zone (SVZ) of the adult brain can undergo cell division and migrate long distances before differentiating into mature neurons.
Yoon, Sung Ok +5 more
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Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements. [PDF]
, 2009 The biology of both normal and tumor development clearly possesses overlapping and parallel features. Oncogenes and tumor suppressors are relevant not only in tumor biology, but also in physiological developmental regulators of growth and differentiation.
Ho, Allen L +4 more
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In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ [PDF]
, 2017 Directed evolution continues to expand the capabilities of complex biomolecules for a range of applications, such as adeno-associated virus vectors for gene therapy; however, advances in library design and selection strategies are key to develop variants
Ojala, David S. +5 more
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