Results 161 to 170 of about 8,183 (195)
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β8 integrin is essential for neuroblast migration in the rostral migratory stream
Glia, 2011AbstractNeurogenesis in the post‐natal brain occurs in two primary locations: the subgranular layer of the hippocampal dentate gyrus and the subventricular zone (SVZ) of the lateral ventricles. Following differentiation, neuroblasts within the SVZ migrate several millimeters to the olfactory bulbs (OBs) via a distinct anatomic route, or rostral ...
Aaron K, Mobley, Joseph H, McCarty
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Astrocytic and Vascular Scaffolding for Neuroblast Migration in the Rostral Migratory Stream
Current Neurovascular Research, 2014New neurons are continuously being added to the olfactory bulb (OB) of adult rodents that are generated in the subventricular zone (SVZ), distant by a few millimeters. Neuronal precursors have to overcome this long distance without the radial-glial migratory scaffold, in contrast to migration mode during embryonic development.
Marcela, Martoncikova +5 more
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Odor enrichment influences neurogenesis in the rostral migratory stream of young rats
Acta Histochemica, 2011The olfactory bulb is one of a few brain structures characterized by high plasticity due to the fact that new neurons are continually integrated into the olfactory bulb circuit throughout life. The new cells originate from the subventricular zone of the forebrain and migrate through the rostral migratory stream (RMS) to the olfactory bulb that also ...
Marcela, Martončíková +4 more
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Ionizing radiation induced long-term alterations in the adult rat rostral migratory stream
Acta Histochemica, 2014Ionizing radiation can induce significant injury to normal brain structures. To assess radiation-induced late effects, adult male Wistar rats received whole-body exposure with fractionated doses of gamma rays (a total dose of 4Gy) and were investigated thirty, sixty and ninety days later.
Sona, Balentova +4 more
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Age-Related Changes of NADPH-Diaphorase Positivity in the Rat Rostral Migratory Stream
Cellular and Molecular Neurobiology, 2005Accumulating evidence confirms that nitric oxide (NO), a versatile diffusible signaling molecule, contributes to controling of adult neurogenesis. We have previously shown the timing of NADPH-diaphorase (NADPH-d) positivity within the rat rostral migratory stream (RMS) during the first postnatal month. The present study was designed to describe further
Enikö, Raceková +4 more
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The rostral migratory stream and olfactory system: smell, disease and slippery cells
2009In the mammalian brain, olfaction is an important sense that is used to detect odors of different kinds that can warn of off food, to produce a mothering instinct in a flock or group of animals, and to warn of danger such as fire or poison. The olfactory system is made up of a long-distance rostral migratory stream that arises from the subventricular ...
Curtis, Maurice +2 more
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Effects of age and strain on cell proliferation in the mouse rostral migratory stream
Neurobiology of Aging, 2013The number of neural progenitor cells (NPCs) decreases with advancing age, and the mechanisms responsible for this decline is unclear. Here, we demonstrate the importance of genetics as a modulator for the age-related decline in NPCs. We systematically quantified the number of proliferating NPCs in the rostral migratory stream, the rostral extension of
Anna, Poon, Dan, Goldowitz
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Neuroscience Letters, 2007
Neural progenitor cells (NPCs) in the subventricular zone (SVZ) travel a long distance along the rostral migratory stream (RMS) to give rise to interneurons in the olfactory bulb (OB). Using the multiphoton microscope and time-lapse recording techniques we here report the behavior of NPCs in the RMS under both intact and ischemic conditions in living ...
Li-Ru, Zhao, Sang Chae, Nam
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Neural progenitor cells (NPCs) in the subventricular zone (SVZ) travel a long distance along the rostral migratory stream (RMS) to give rise to interneurons in the olfactory bulb (OB). Using the multiphoton microscope and time-lapse recording techniques we here report the behavior of NPCs in the RMS under both intact and ischemic conditions in living ...
Li-Ru, Zhao, Sang Chae, Nam
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Cell Proliferation in the Adult Rat Rostral Migratory Stream Following Exposure to Gamma Irradiation
Cellular and Molecular Neurobiology, 2006One of the few areas of the adult CNS, that are known to be competent for neuronal proliferation, is the subventricular zone (SVZ) lining the brain lateral ventricles. Cells proliferating in the SVZ migrate along a defined pathway, the rostral migratory stream (RMS), where their proliferation continues until reaching the olfactory bulb. 1.
Sona, Bálentová +3 more
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GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream
Molecular and Cellular Neuroscience, 2006Olfactory bulb (OB) interneurons are generated from neuroblast cells derived from the anterior subventricular zone (SVZa) of the forebrain. The mechanisms guiding the rostral migration of these neuronal precursors are not well understood. Here, we show that glial cell line-derived neurotrophic factor (GDNF) is produced in the olfactory bulb but ...
Gustavo, Paratcha +2 more
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