Results 11 to 20 of about 8,183 (195)

Delayed maturation and altered proliferation within the rat rostral migratory stream following maternal deprivation [PDF]

European Journal of Histochemistry, 2011
The objective of this study was to investigate whether stressful experience during early postnatal period may influence morphological characteristics of the rat neurogenic pathway – the rostral migratory stream (RMS) and proliferation of neuronal ...
K. Lievajova, J. Blasko, M. Martoncikova, V. Cigankova, E. Racekova   +4 more
doaj   +5 more sources

Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream. [PDF]

Sci Rep, 2016
The subventricular zone (SVZ) provides a constant supply of new neurons to the olfactory bulb (OB). Different studies have investigated the role of olfactory sensory input to neural precursor cell (NPC) turnover in the SVZ but it was not addressed if ...
Langenfurth A, Gu S, Bautze V, Zhang C, Neumann JE, Schüller U, Stock K, Wolf SA, Maier AM, Mastrella G, Pak A, Cheng H, Kälin RE, Holmbeck K, Strotmann J, Kettenmann H, Glass R.   +16 more
europepmc   +5 more sources

Specialized Vasculature in the Rostral Migratory Stream as a Neurogenic Niche and Scaffold for Neuroblast Migration [PDF]

Cell Transplantation, 2015
Neurovascular niches serve as the hosts for adult neural stem cells in both the hippocampus and subventricular zone. The rostral migratory stream (RMS) vasculature has been found to be important for neuroblast migration, while its roles in hosting ...
Ti-Fei Yuan, Yu-Xiang Liang, David Tay, Kwok-Fai So Ph.D., Rutledge Ellis-Behnke Ph.D.   +4 more
doaj   +2 more sources

The rostral migratory stream generates hippocampal CA1 pyramidal-like neurons in a novel organotypic slice co-culture model [PDF]

Biology Open, 2015
The mouse subventricular zone (SVZ) generates large numbers of neuroblasts, which migrate in a distinct pathway, the rostral migratory stream (RMS), and replace specific interneurons in the olfactory bulb (OB).
Ilyas Singec, Rolf Knoth, Imre Vida, Michael Frotscher   +3 more
doaj   +2 more sources

Subventricular zone cell migration: lessons from quantitative 2-photon microscopy [PDF]

Frontiers in Neuroscience, 2011
Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons.
Rachel eJames, Yongsoo eKim, Philip eHockberger, Francis G Szele   +3 more
doaj   +3 more sources

The rostral migratory stream plays a key role in intranasal delivery of drugs into the CNS. [PDF]

PLoS ONE, 2011
The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into
Robert A Scranton, Lauren Fletcher, Shane Sprague, David F Jimenez, Murat Digicaylioglu   +4 more
doaj   +2 more sources

Microglia Maintain Homeostatic Conditions in the Developing Rostral Migratory Stream. [PDF]

eNeuro, 2023
Microglia invade the neuroblast migratory corridor of the rostral migratory stream (RMS) early in development. The early postnatal RMS does not yet have the dense astrocyte and vascular scaffold that helps propel forward migrating neuroblasts, which led us to consider whether microglia help regulate conditions permissive to ...
Meller SJ, Hernandez L, Martin-Lopez E, Kloos ZA, Liberia T, Greer CA.   +5 more
europepmc   +3 more sources

Morphological evidence for neuronal connections between the olfactory neurogenic region and the striatum in adult rats [PDF]

Frontiers in Neural Circuits
The regulatory mechanisms of postnatal neurogenesis in the subventricular zone (SVZ) and the rostral migratory stream (RMS) are still not fully understood.
Kamila Fabianová, Marcela Martončíková, Ivo Vanický, Juraj Blaško, Alexandra Popovičová, Monika Žideková, Enikő Račeková   +6 more
doaj   +2 more sources

Neuronal migration depends on blood flow in the adult mammalian brain [PDF]

eLife
In animal tissues, several cell types migrate along blood vessels, raising the possibility that blood flow influences cell migration. Here, we show that blood flow promotes the migration of new olfactory-bulb neurons in the adult mammalian brain ...
Takashi Ogino, Akari Saito, Masato Sawada, Shoko Takemura, Yuzuki Hara, Kanami Yoshimura, Jiro Nagase, Honomi Kawase, Takamasa Sato, Hiroyuki Inada, Vicente Herranz-Pérez, Yoh-suke Mukouyama, Masatsugu Ema, José Manuel García-Verdugo, Junichi Nabekura, Kazunobu Sawamoto   +15 more
doaj   +2 more sources

Developmental regulation of long-range neuroblast migration by Eph/ephrin signaling [PDF]

Frontiers in Neuroscience
In the developing mouse anterior forebrain, the rostral migratory stream (RMS) supports continued proliferation and efficient transportation of large quantities of neuroblasts from the ventricular-subventricular (V-SVZ) stem cell niche to the olfactory ...
Daria Yeroshenko, Chamalka de Silva, Anika Burli, Sarah Bellizzi, Vijender Singh, Joanne Conover   +5 more
doaj   +2 more sources