Age-dependent regional changes in the rostral migratory stream. [PDF]
Neurobiol Aging, 2013 Throughout life the subventricular zone (SVZ) is a source of new olfactory bulb (OB) interneurons. From the SVZ, neuroblasts migrate tangentially through the rostral migratory stream (RMS), a restricted route approximately 5 mm long in mice, reaching the OB within 10-14 days.
Mobley AS +5 more
europepmc +7 more sources
KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo. [PDF]
Cereb Cortex, 2014 From the subventricular zone (SVZ), neuronal precursor cells (NPCs), called neuroblasts, migrate through the rostral migratory stream (RMS) to become interneurons in the olfactory bulb (OB). Ion channels regulate neuronal migration during development, yet their role in migration through the adult RMS is unknown.
Turner KL, Sontheimer H.
europepmc +6 more sources
A three-dimensional tissue-engineered rostral migratory stream as an in vitro platform for subventricular zone-derived cell migration [PDF]
Frontiers in Bioengineering and BiotechnologyIn the brains of most adult mammals, neural precursor cells (NPCs) from the subventricular zone (SVZ) migrate through the rostral migratory stream (RMS) to replace olfactory bulb interneurons.
Erin M. Purvis +12 more
doaj +4 more sources
Blood vessels form a migratory scaffold in the rostral migratory stream. [PDF]
J Comp Neurol, 2009 AbstractIn adult mice, new neurons born in the subventricular zone (SVZ), lining the lateral ventricles, migrate tangentially into the olfactory bulb along a well‐delineated path, the rostral migratory stream (RMS). Neuroblasts in the RMS migrate tangentially in chains, without a recognized migratory scaffold.
Whitman MC +4 more
europepmc +7 more sources
Specialized Vasculature in the Rostral Migratory Stream as a Neurogenic Niche and Scaffold for Neuroblast Migration [PDF]
Cell Transplantation, 2015 Neurovascular niches serve as the hosts for adult neural stem cells in both the hippocampus and subventricular zone. The rostral migratory stream (RMS) vasculature has been found to be important for neuroblast migration, while its roles in hosting ...
Ti-Fei Yuan +4 more
doaj +4 more sources
EndoN treatment allows neuroblasts to leave the rostral migratory stream and migrate towards a lesion within the prefrontal cortex of rats [PDF]
Neural Regeneration Research, 2020 The binding properties of neural cell adhesion molecule are modulated by a polysialic acid moiety. This plays an important role in the migration of adult born neuroblasts from their area of origin, the subventricular zone, towards the olfactory bulb ...
Jannis Gundelach, Michael Koch
doaj +2 more sources
Effect of methotrexate on rostral migratory stream in newborn rats. [PDF]
J Vet Med Sci, 2016 Two-day-old rats were treated with subcutaneous injections of methotrexate (MTX) 5 mg/kg and 150 mg/kg, and their rostral migratory streams (RMS) were examined time-dependently. MTX treatment increased pyknotic and TUNEL-positive cells and decreased mitotic and phospho-Histone H3-positive cells at almost all time points in the vertical arm, elbow and ...
Hirako A +4 more
europepmc +4 more sources
Clonal Mapping of Astrocytes in the Olfactory Bulb and Rostral Migratory Stream. [PDF]
Cereb Cortex, 2017 Astrocytes are the most abundant glial population in the central nervous system, where they fulfill multiple essential tasks. Such diverse functions require a heterogeneous population of cells, yet it is still unclear how this cellular heterogeneity emerges during development.
García-Marqués J, López-Mascaraque L.
europepmc +5 more sources
Unique Astrocyte Cytoskeletal and Nuclear Morphology in a Three-Dimensional Tissue-Engineered Rostral Migratory Stream. [PDF]
Neuroglia, 2022 Neural precursor cells (NPCs) are generated in the subventricular zone (SVZ) and travel through the rostral migratory stream (RMS) to replace olfactory bulb interneurons in the brains of most adult mammals. Following brain injury, SVZ-derived NPCs can divert from the RMS and migrate toward injured brain regions but arrive in numbers too low to promote ...
Purvis EM, O'Donnell JC, Cullen DK.
europepmc +4 more sources
Early stress affects neurogenesis in the rat rostral migratory stream
Open Life Sciences, 2010 Abstract Stressful experience during the early postnatal period may influence processes associated with neurogenesis (i.e. proliferation, cell death, appearance of astrocytes or cell differentiation) in the neonatal rat rostral migratory stream (RMS).
Lievajová Kamila +5 more
doaj +2 more sources