Results 21 to 30 of about 8,077 (182)

Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream. [PDF]

Sci Rep, 2016
The subventricular zone (SVZ) provides a constant supply of new neurons to the olfactory bulb (OB). Different studies have investigated the role of olfactory sensory input to neural precursor cell (NPC) turnover in the SVZ but it was not addressed if ...
Langenfurth A, Gu S, Bautze V, Zhang C, Neumann JE, Schüller U, Stock K, Wolf SA, Maier AM, Mastrella G, Pak A, Cheng H, Kälin RE, Holmbeck K, Strotmann J, Kettenmann H, Glass R.   +16 more
europepmc   +5 more sources

Rostral migratory stream neuroblasts turn and change directions in stereotypic patterns. [PDF]

Cell Adh Migr, 2011
Neuroblasts generated in the adult subventricular zone (SVZ) migrate through the rostral migratory stream (RMS) to the olfactory bulb (OB). Previous work uncovered motility ranging from straight to complex, but it was unclear if directional changes were stochastic or exhibited stereotypical patterns.
Martinez-Molina N, Kim Y, Hockberger P, Szele FG.   +3 more
europepmc   +4 more sources

The rostral migratory stream generates hippocampal CA1 pyramidal-like neurons in a novel organotypic slice co-culture model [PDF]

Biology Open, 2015
The mouse subventricular zone (SVZ) generates large numbers of neuroblasts, which migrate in a distinct pathway, the rostral migratory stream (RMS), and replace specific interneurons in the olfactory bulb (OB).
Ilyas Singec, Rolf Knoth, Imre Vida, Michael Frotscher   +3 more
doaj   +2 more sources

Visualization of Rostral Migratory Stream in the Developing Rat Brain by In Vivo Electroporation. [PDF]

Cell Mol Neurobiol, 2018
Interneurons in the olfactory bulb (OB) are generated from neuronal precursor cells migrating from anterior subventricular zone (SVZa) not only in the developing embryo but also throughout the postnatal life of mammals. In the present study, we established an in vivo electroporation assay to label SVZa cells of rat both at embryonic and postnatal ages,
Xie YW, Li ZY, Du J, Chen Y, Chen BY, Wang TT, Huang Z, Hou S, Wang Y.   +8 more
europepmc   +3 more sources

Subventricular zone cell migration: lessons from quantitative 2-photon microscopy [PDF]

Frontiers in Neuroscience, 2011
Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons.
Rachel eJames, Yongsoo eKim, Philip eHockberger, Francis G Szele   +3 more
doaj   +3 more sources

The rostral migratory stream plays a key role in intranasal delivery of drugs into the CNS. [PDF]

PLoS ONE, 2011
The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into
Robert A Scranton, Lauren Fletcher, Shane Sprague, David F Jimenez, Murat Digicaylioglu   +4 more
doaj   +2 more sources

Maternal separation induced alterations of neurogenesis in the rat rostral migratory stream. [PDF]

Cell Mol Neurobiol, 2009
1. The aim of our study was to investigate the possibility that maternal separation, an experimental model for studies of early environmental influences, has an effect on postnatal neurogenesis in neurogenic pathway--the rostral migratory stream (RMS). 2.
Raceková E, Lievajová K, Danko J, Martoncíková M, Flesárová S, Almasiová V, Orendácová J.   +6 more
europepmc   +3 more sources

Morphological evidence for neuronal connections between the olfactory neurogenic region and the striatum in adult rats [PDF]

Frontiers in Neural Circuits
The regulatory mechanisms of postnatal neurogenesis in the subventricular zone (SVZ) and the rostral migratory stream (RMS) are still not fully understood.
Kamila Fabianová, Marcela Martončíková, Ivo Vanický, Juraj Blaško, Alexandra Popovičová, Monika Žideková, Enikő Račeková   +6 more
doaj   +2 more sources

Neuronal migration depends on blood flow in the adult mammalian brain [PDF]

eLife
In animal tissues, several cell types migrate along blood vessels, raising the possibility that blood flow influences cell migration. Here, we show that blood flow promotes the migration of new olfactory-bulb neurons in the adult mammalian brain ...
Takashi Ogino, Akari Saito, Masato Sawada, Shoko Takemura, Yuzuki Hara, Kanami Yoshimura, Jiro Nagase, Honomi Kawase, Takamasa Sato, Hiroyuki Inada, Vicente Herranz-Pérez, Yoh-suke Mukouyama, Masatsugu Ema, José Manuel García-Verdugo, Junichi Nabekura, Kazunobu Sawamoto   +15 more
doaj   +2 more sources

ADAM2 promotes migration of neuroblasts in the rostral migratory stream to the olfactory bulb. [PDF]

Eur J Neurosci, 2008
AbstractNeuroblasts migrate from the subventricular zone along the rostral migratory stream (RMS) to the olfactory bulb (OB). While the migration occurs by movement over other cells, the molecular mechanisms are poorly understood. We have found that ADAM2 (a disintegrin and metalloprotease 2) is expressed in migrating RMS neuroblasts and functions in ...
Murase S, Cho C, White JM, Horwitz AF.
europepmc   +4 more sources