Early stress affects neurogenesis in the rat rostral migratory stream
Abstract Stressful experience during the early postnatal period may influence processes associated with neurogenesis (i.e. proliferation, cell death, appearance of astrocytes or cell differentiation) in the neonatal rat rostral migratory stream (RMS).
Lievajová Kamila +5 more
doaj +2 more sources
Effect of methotrexate on rostral migratory stream in newborn rats. [PDF]
Two-day-old rats were treated with subcutaneous injections of methotrexate (MTX) 5 mg/kg and 150 mg/kg, and their rostral migratory streams (RMS) were examined time-dependently. MTX treatment increased pyknotic and TUNEL-positive cells and decreased mitotic and phospho-Histone H3-positive cells at almost all time points in the vertical arm, elbow and ...
Hirako A +4 more
europepmc +4 more sources
Clonal Mapping of Astrocytes in the Olfactory Bulb and Rostral Migratory Stream. [PDF]
Astrocytes are the most abundant glial population in the central nervous system, where they fulfill multiple essential tasks. Such diverse functions require a heterogeneous population of cells, yet it is still unclear how this cellular heterogeneity emerges during development.
García-Marqués J, López-Mascaraque L.
europepmc +5 more sources
Age-dependent regional changes in the rostral migratory stream. [PDF]
Throughout life the subventricular zone (SVZ) is a source of new olfactory bulb (OB) interneurons. From the SVZ, neuroblasts migrate tangentially through the rostral migratory stream (RMS), a restricted route approximately 5 mm long in mice, reaching the OB within 10-14 days.
Mobley AS +5 more
europepmc +5 more sources
Unique Astrocyte Cytoskeletal and Nuclear Morphology in a Three-Dimensional Tissue-Engineered Rostral Migratory Stream. [PDF]
Neural precursor cells (NPCs) are generated in the subventricular zone (SVZ) and travel through the rostral migratory stream (RMS) to replace olfactory bulb interneurons in the brains of most adult mammals. Following brain injury, SVZ-derived NPCs can divert from the RMS and migrate toward injured brain regions but arrive in numbers too low to promote ...
Purvis EM, O'Donnell JC, Cullen DK.
europepmc +4 more sources
Blood vessels form a migratory scaffold in the rostral migratory stream. [PDF]
AbstractIn adult mice, new neurons born in the subventricular zone (SVZ), lining the lateral ventricles, migrate tangentially into the olfactory bulb along a well‐delineated path, the rostral migratory stream (RMS). Neuroblasts in the RMS migrate tangentially in chains, without a recognized migratory scaffold.
Whitman MC +4 more
europepmc +5 more sources
Cell Migration in the Rostral Migratory Stream [PDF]
Adult neurogenesis in the olfactory bulb of rodents is provided by cells which migrate tangentially from their site of genesis into the forebrain subependymal layer (SEL). This migration involves 'chains' of neuroblasts sliding into a meshwork of astrocytic cells and processes (glial tubes).
FASOLO, Aldo +2 more
openaire +3 more sources
KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo. [PDF]
From the subventricular zone (SVZ), neuronal precursor cells (NPCs), called neuroblasts, migrate through the rostral migratory stream (RMS) to become interneurons in the olfactory bulb (OB). Ion channels regulate neuronal migration during development, yet their role in migration through the adult RMS is unknown.
Turner KL, Sontheimer H.
europepmc +4 more sources
Rostral migratory stream neuroblasts turn and change directions in stereotypic patterns. [PDF]
Neuroblasts generated in the adult subventricular zone (SVZ) migrate through the rostral migratory stream (RMS) to the olfactory bulb (OB). Previous work uncovered motility ranging from straight to complex, but it was unclear if directional changes were stochastic or exhibited stereotypical patterns.
Martinez-Molina N +3 more
europepmc +4 more sources
Visualization of Rostral Migratory Stream in the Developing Rat Brain by In Vivo Electroporation. [PDF]
Interneurons in the olfactory bulb (OB) are generated from neuronal precursor cells migrating from anterior subventricular zone (SVZa) not only in the developing embryo but also throughout the postnatal life of mammals. In the present study, we established an in vivo electroporation assay to label SVZa cells of rat both at embryonic and postnatal ages,
Xie YW +8 more
europepmc +3 more sources

