Results 31 to 40 of about 8,183 (195)

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus [PDF]

, 2016
Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents.
Blazer-Yost, Bonnie L., Hameed, Mustafa Q., Klagsbrun, Michael, Madsen, Joseph R., Sandlund, Johanna, Shim, Joon W., Zhou, Feng C.   +6 more
core   +2 more sources

Tissue Engineering and Biomaterial Strategies to Elicit Endogenous Neuronal Replacement in the Brain

Frontiers in Neurology, 2020
Neurogenesis in the postnatal mammalian brain is known to occur in the dentate gyrus of the hippocampus and the subventricular zone. These neurogenic niches serve as endogenous sources of neural precursor cells that could potentially replace neurons that
Erin M. Purvis, Erin M. Purvis, John C. O'Donnell, John C. O'Donnell, H. Isaac Chen, H. Isaac Chen, D. Kacy Cullen, D. Kacy Cullen, D. Kacy Cullen   +8 more
doaj   +1 more source

Cell proliferation and neurogenesis in adult mouse brain. [PDF]

PLoS ONE, 2014
Neurogenesis, the formation of new neurons, can be observed in the adult brain of many mammalian species, including humans. Despite significant progress in our understanding of adult neurogenesis, we are still missing data about the extent and location ...
Olivia L Bordiuk, Karen Smith, Peter J Morin, Mikhail V Semënov   +3 more
doaj   +1 more source

Maternal separation induced alterations of neurogenesis in the rat rostral migratory stream. [PDF]

Cell Mol Neurobiol, 2009
1. The aim of our study was to investigate the possibility that maternal separation, an experimental model for studies of early environmental influences, has an effect on postnatal neurogenesis in neurogenic pathway--the rostral migratory stream (RMS). 2.
Raceková E, Lievajová K, Danko J, Martoncíková M, Flesárová S, Almasiová V, Orendácová J.   +6 more
europepmc   +3 more sources

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia [PDF]

, 2009
The peripheral nervous system (PNS) of higher vertebrates is segmented to align the spinal nerve roots with the vertebrae. This co-patterning is set up during embryogenesis, when vertebrae develop from the sclerotome layer of the metameric somites, and ...
Davidson, K, Maden, CH, Ruhrberg, C, Schwarz, Q   +3 more
core   +2 more sources

Neuronal migration in the murine rostral migratory stream requires serum response factor [PDF]

Proceedings of the National Academy of Sciences, 2005
The central nervous system is fundamentally dependent on guided cell migration, both during development and in adulthood. We report an absolute requirement of the transcription factor serum response factor (SRF) for neuronal migration in the mouse forebrain. Conditional, late-prenatal deletion of Srf
Alberti, Siegfried, Krause, Sven M., Kretz, Oliver, Philippar, Ulrike, Lemberger, Thomas, Casanova, Emilio, Wiebel, Franziska F., Schwarz, Heinz, Frotscher, Michael, Schütz, Günther, Nordheim, Alfred   +10 more
openaire   +4 more sources

Evidence of a Cell Surface Role for Hsp90 Complex Proteins Mediating Neuroblast Migration in the Subventricular Zone

Frontiers in Cellular Neuroscience, 2017
In most mammalian brains, the subventricular zone (SVZ) is a germinative layer that maintains neurogenic activity throughout adulthood. Neuronal precursors arising from this region migrate through the rostral migratory stream (RMS) and reach the ...
Leo M. Miyakoshi, Leo M. Miyakoshi, Diego Marques-Coelho, Diego Marques-Coelho, Luiz E. R. De Souza, Flavia R. S. Lima, Vilma R. Martins, Silvio M. Zanata, Cecilia Hedin-Pereira, Cecilia Hedin-Pereira, Cecilia Hedin-Pereira   +10 more
doaj   +1 more source

Cellular Organization and Migration Pathways of the Ventricular-Subventricular Zone in the Juvenile Swine Brain (Sus scrofa domesticus). [PDF]

J Comp Neurol
A detailed structural analysis of the juvenile swine ventricular–subventricular zone reveals four distinct cellular layers and diverse neuroblast migration routes, including pathways toward the olfactory bulb and cortical regions. These features underscore the swine brain's value as a translational model for studying postnatal neurogenesis in large ...
Torrijos-Saiz LI, Freixes J, Desfilis E, Medina L, Sawamoto K, García-Verdugo JM, Herranz-Pérez V.   +6 more
europepmc   +2 more sources

Subependymal Zone: Immunohistochemically Distinct Compartment in the Adult Mammalian Forebrain

Acta Medica, 2004
The subependymal zone (SEZ) lining lateral walls of the lateral cerebral ventricles represents the site of active neurogenesis in the brain of adult mammals.
Jaroslav Mokrý, Dana Čížková, Jan Österreicher   +2 more
doaj   +1 more source

The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

eLife, 2020
Cell migration is a dynamic process that entails extensive protein synthesis and recycling, structural remodeling, and considerable bioenergetic demand. Autophagy is one of the pathways that maintain cellular homeostasis.
Cedric Bressan, Alessandra Pecora, Dave Gagnon, Marina Snapyan, Simon Labrecque, Paul De Koninck, Martin Parent, Armen Saghatelyan   +7 more
doaj   +1 more source