Results 51 to 60 of about 58,009 (170)

Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia

eLife, 2022
Pain perception is decreased by shifting attentional focus away from a threatening event. This attentional analgesia engages parallel descending control pathways from anterior cingulate (ACC) to locus coeruleus, and ACC to periaqueductal grey (PAG ...
Valeria Oliva, Ron Hartley-Davies, Rosalyn Moran, Anthony E Pickering, Jonathan CW Brooks   +4 more
doaj   +1 more source

Cranial anatomy of a Late Cretaceous aspidorhynchid fish (Neopterygii: Aspidorhynchiformes) from Alberta, Canada

The Anatomical Record, Volume 309, Issue 11, Page 3123-3136, November 2026.
Abstract Belonostomus longirostrisis was named for an isolated jaw fragment from freshwater Upper Cretaceous (Campanian) sediments of the Dinosaur Park Formation of Alberta, Canada. Following the description of the Albertan species, numerous isolated cranial and postcranial elements have been collected from the Dinosaur Park Formation and assigned to B.
Mondo Miyazato, Luke E. Nelson, Joshua A. Doyon, Donald B. Brinkman, Alison M. Murray   +4 more
wiley   +1 more source

Activity of most rostral ventromedial medulla neurons reflect EEG/EMG pattern changes

, 1989
Studies in lightly anesthetized animals have demonstrated neurons in the rostral ventromedial medulla (RVM) that respond to specific modalities of peripheral stimulation.
H. C. Heller, D. A. Grahn
core   +1 more source

Targeting peroxynitrite production in a model of persistent temporomandibular disorder comorbid with migraine

British Journal of Pharmacology, Volume 183, Issue 21, Page 6371-6385, November 2026.
Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman, Ana Belen Salinas‐Abarca, Wei Guo, Daniela Salvemini, Marcela Romero‐Reyes   +4 more
wiley   +1 more source

The right temperature at the right time: A framework for understanding thermoregulatory pathophysiology in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract The neuromodulatory subcortical system (NSS) includes thermoregulatory neurons that maintain core body temperature (Tb) and brain temperature within a narrow, diurnally varying range. Cellular pathways in NSS neurons implicated in Alzheimer's disease (AD) may be vulnerable to Tb rhythm disturbance because of their sensitivity to temperature ...
Esther Blessing
wiley   +1 more source

Identification of cardiovascular neurons in the rostral ventromedial medulla in anesthetized rats. [PDF]

Hypertension, 1992
Recent studies have identified a region in the rostral ventromedial medulla (RVMM) of rats that appears to be involved in cardiovascular function. Since these studies used either microinjection of lidocaine or electrical stimulation, the exact contribution of intrinsic neurons as opposed to fibers of passage could not be determined.
K J, Varner, D S, Rutherford, E C, Vasquez, M J, Brody   +3 more
openaire   +2 more sources

The distribution patterns of neurons in the spinal cord that were retrogradely labeled from the rostral ventromedial medulla.

, 2013
Schematic drawings showing the brainstems of three rats with fluorescent microsphere injections (blue, purple and red) and the corresponding spinal cords with the distribution of retrogradely labeled neurons (filled black circles), and retrogradely ...
Somesh K. Kohli (324278), Mehdi Hossaini (324275), Jan C. Holstege (324281), Jacqueline A. C. Goos (324276)   +3 more
core   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

How Affective States Moderate the Relationship of Pain Catastrophizing With Pain Severity in Patients With Acute and Chronic Pain

Brain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Background Psychological factors, including mood, affect, and pain catastrophizing, critically influence pain perception. We aimed to examine the relationships of these factors with pain trajectories in both acute postsurgical pain (APSP) and chronic non‐cancer pain (CNCP) cohorts.
Quinte T. Y. Kuper, Jasmijn E. Willemen, Richel Lousberg, Ruud J. M. Severeijns, Therese A. M. J. van Amelsvoort, Andrea J. R. Balthasar   +5 more
wiley   +1 more source

Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice

, 2015
The molecular mechanism of action of dipyrone, a widely used antipyretic and non-opioid analgesic drug, is still not fully understood. Actions upon peripheral inflamed tissues as well as the central nervous system, especially upon the PAG-RVM axis, have ...
Imming P., Luongo L., De Gregorio D., Maione S., Di Marzo V., De Petrocellis L., Radanova L., Luongo L, Radanova L, Di Marzo V, Imming P, De Gregorio D, Maione S, De Petrocellis L   +13 more
core   +1 more source