Results 51 to 60 of about 63,875 (265)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PhotonicsThe cooling of a macroscopic mechanical oscillator to its quantum ground state is an important step for achieving coherent control over mechanical quantum states.
Xinyue Cao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Nonlinear Normal Modes of a Rotating Shaft Based on the Invariant Manifold Method
International Journal of Rotating Machinery, 2004 The nonlinear normal mode methodology is generalized to the study of a rotating shaft supported by two short journal bearings. For rotating shafts, nonlinearities are generated by forces arising from the supporting hydraulic bearings.
Mathias Legrand +3 more
doaj +1 more source
Design of online fault diagnosis and early warning system for coal mine rotating machinery
Gong-kuang zidonghua, 2019 In view of problems that existing coal mine machinery online monitoring and diagnosis technology did not realize online extraction of fault characteristics and automatic identification of fault types, an online fault diagnosis and early warning system ...
YANG Yiqing +5 more
doaj +1 more source
Resonance of Fofonoff's Mode in a Rotated Basin
Journal of Physical Oceanography, 1993 Abstract Fofonoff solutions to the inviscid barotropic potential vorticity equation are found for the steady, free flow in a basin rotated at an arbitrary angle to a latitude circle. These solutions am used to study the inertial recirculation of the subtropical gyre, which is forced by anomalously low values of potential vorticity within the separated ...
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Case Study of Pump Failure Due to Rotor-Stator Interaction
International Journal of Rotating Machinery, 1994 Fluiddynamic interaction between rotor and stator generates local pressure fluctuation and can be a cause ofstructural vibration of turbomachines. The interaction produces a spatial distribution of pressure fluctuation with a certain diametrical mode ...
Hideo Ohashi
doaj +1 more source
Fast rotation and acoustic modes
Bulletin de la Société Royale des Sciences de Liège, 2020 In this contribution, we describe recent progress in modelling acoustic pulsations of rapidly rotating stars. We then go on to describe very recent attempts at interpreting pulsation spectra in two observed stars. These make use of multi-colour mode visibilities, mode excitation, and pulsation frequencies in order to con-strain the identification of ...
openaire +3 more sources
Rotational modes of relativistic stars: Analytic results [PDF]
Physical Review D, 2000 36 pages revtex v3.1, 2 eps ...
Lockitch, Keith H. +2 more
openaire +3 more sources