Results 61 to 70 of about 2,634,553 (326)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
New Technique: A Novel Femoral Derotation Osteotomy for Malrotation following Intramedullary Nailing
Case Reports in Orthopedics, 2012 A 19-year-old female patient sustained a closed spiral midshaft femoral fracture and subsequently underwent femoral intramedullary nail insertion. At followup she complained of difficulty in walking and was found to have a unilateral in-toeing gait.
S. Jagernauth +3 more
doaj +1 more source
, 2012 Two classes of conservative, linear, optical rotary effects (optical activity and Faraday rotation) are distinguished by their behavior under time reversal.
Andrews, James H. +2 more
core +1 more source
First CMB Constraints on Direction-Dependent Cosmological Birefringence from WMAP-7 [PDF]
, 2012 A Chern-Simons coupling of a new scalar field to electromagnetism may give rise to cosmological birefringence, a rotation of the linear polarization of electromagnetic waves as they propagate over cosmological distances.
Gluscevic, Vera +3 more
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Design and Vibration Characteristic Analysis of Piezoelectric Micro Oil-Supply Device
Applied SciencesIn response to the lubrication failure problem during spacecraft operation, new requirements have been put forward for micro, precise, and dynamically adjustable lubrication and oil-supply technology for its key moving components. This article charts the
Zhaoliang Dou +5 more
doaj +1 more source
The Physics Teacher, 1998 We discuss two basic properties of angular displacements, namely, the anticommutation of finite rotations, and the commutation of infinitesimal rotations, and show how commutation is achieved as the angular displacement gets smaller and smaller.
J. A. da Silva Neto, Oscar Bolina
openaire +2 more sources
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Journal of Orthopaedic ReportsBackground: The first aim of this study was to report the authors’ experience in the last 10 years, for arthroscopic ankle fusion in haemophilic ankle arthropathy.
Fitzgerald Chukwuemeka Anazor +3 more
doaj +1 more source
On Rotation Curve Analysis [PDF]
, 2018 An analysis of analytical methods used for computing galactic masses on the basis of rotation curves (Saari 2015) is shown to be ...
Kadowaki, Kevin
core +1 more source