Results 81 to 90 of about 2,719,005 (328)

Defective wing development in black-headed gull (Larus ridibundus) - case report

open access: yesVeterinární Medicína, 2003
In 2000-2001 juvenile individuals of black-headed gull (Larus ridibundus) were repeatedly found in a Nadeje fishpond system in the Trebon Basin Area that were incapable of flying, with deformed wings.
J. Rajchard, V. Rajchard
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A simple novel technique for closure of simple and complex pilonidal sinus with either simple (tongueshaped) or bilobed rotation fl ap

open access: yesIndian Journal of Plastic Surgery, 2007
Background:Pilonidal sinus is a common disease in young adults that carries high postoperative morbidity and patients′ discomfort; controversy still exists regarding the best surgical technique for the treatment of the disease.
M.S. Awad Mohamed   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Acoustic rotation control [PDF]

open access: yes, 1983
A system is described for acoustically controlled rotation of a levitated object, which avoids deformation of a levitated liquid object. Acoustic waves of the same wavelength are directed along perpendicular directions across the object, and with the ...
Croonquist, A. P.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Phase-lag and diffusion in porous thermoelastic micropolar media with initial pressure and rotational forces affected by modified Ohm’s law and gravity [PDF]

open access: yesSINAI International Scientific Journal
This study explores the diffusion in micropolar thermoelastic materials with voids rotating at a uniform angular velocity. Researchers utilized the harmonic solution as an analytical method to examine the micropolar porous medium affected by gravity and ...
Mohamed Hilal, Ahmed Shehata
doaj   +1 more source

ROTATING GLOBULAR CLUSTERS [PDF]

open access: yesThe Astrophysical Journal, 2013
Internal rotation is considered to play a major role in the dynamics of some globular clusters. However, in only few cases it has been studied by quantitative application of realistic and physically justified global models. Here we present a dynamical analysis of the photometry and three-dimensional kinematics of omega Cen, 47 Tuc, and M15, by means of
P. Bianchini   +3 more
openaire   +2 more sources

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