Results 51 to 60 of about 1,601,631 (247)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Protonation of apolar species: From Cl2H+ to (E)-NCCHCHCNH+ through computational investigations
Radioastronomy is a powerful tool for the discovery of molecules in space but it requires molecular species to be polar. The observation of apolar species can be however enabled by protonation, which occurs from reaction with the abundant H3+ ion ...
Silvia Alessandrini +3 more
doaj +1 more source
Broadband rotational spectroscopy [PDF]
The past decade has seen several major technology advances in electronics operating at microwave frequencies making it possible to develop a new generation of spectrometers for molecular rotational spectroscopy.
Brooks Pate, Pate, Brooks
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The gas-phase structures of the fruit ester methyl hexanoate, CH3-O-(C=O)-C5H11, have been determined using a combination of molecular jet Fourier-transform microwave spectroscopy and quantum chemistry.
Nhu-Ngoc Dang +5 more
doaj +1 more source
Rotational spectroscopy for astrophysical investigations
This account is an attempt of providing a brief, but exhaustive overview on the possible applications of rotational spectroscopy in the field of astrophysics and ...
Cristina Puzzarini, PUZZARINI, CRISTINA
core +2 more sources
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
1) Introductory lecture on rotational spectroscopy 2) Rotational spectroscopy at work
1) Introductory lecture on rotational spectroscopy 2) Rotational spectroscopy at ...
PUZZARINI, CRISTINA
core +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source

