Results 61 to 70 of about 1,499,763 (298)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular size limits for rotational spectroscopy and the high-J limit of the rigid rotor [PDF]
Made available in DSpace on 2019-07-15T22:17:03Z (GMT). No. of bitstreams: 2 4086.pdf: 15272 bytes, checksum: 6d41aac8fba840333bd82965a2cb7715 (MD5) license.txt: 4802 bytes, checksum: 58353f9dd6876860dd5221f3d7872a95 (MD5) Previous issue date: 2019-06 ...
Pate, Brooks
core +1 more source
Terahertz Rotational Spectroscopy of Greenhouse Gases Using Long Interaction Path-Lengths
Even if on-board mm-wave/THz heterodyne receivers have been developed to measure greenhouse gases (GHGs) atmospheric profiles, rotational spectroscopy rests under-exploited for their monitoring unlike IR rovibrational spectroscopy.
Arnaud Cuisset +9 more
doaj +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Ultrafast non-linear time-resolved spectroscopy : application to the structural study of polyatomic molecules and clusters [PDF]
A new experimental setup, for pump-probe fs DFWM measurements, which is based on a femtosecond laser system, has been constructed. It allows for the investigation of molecular species in the gas phase at different temperatures, from ~30 K in a seeded ...
Matylitsky, Victor V.
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Quantitative chiral analysis by molecular rotational spectroscopy
Recent advances in the application of molecular rotational spectroscopy to chiral analysis are described. These include the use of broadband rotational spectroscopy for the analysis of diastereomers of molecules with multiple chiral centers.
Schnell, Melanie +15 more
core +1 more source
The structure and interactions of oxygenated aromatic molecules are of atmospheric interest due to their toxicity and as precursors of aerosols. Here, we present the analysis of 4-methyl-2-nitrophenol (4MNP) using chirped pulse and Fabry–Pérot Fourier ...
Shefali Baweja +6 more
doaj +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Laser spectroscopy and ab initio calculations on the TaF Molecule [PDF]
Electronic transition spectrum of the tantalum monoflouride (TaF) molecule in the spectral region between 448 and 520 nm has been studied using the technique of laser-ablation/reaction free jet expansion and laser induced fluorescence spectroscopy.
Ng, KF +7 more
core +1 more source

