Results 61 to 70 of about 48,570 (189)
Acute gastroenteritis associated with Rotavirus A among children less than 5 years of age in Nepal
Background Rotavirus gastroenteritis is a major public health problem in Nepal. This study was conducted to obtain information associated with Rotavirus gastroenteritis and to perform genotyping of Rotavirus A.
Sony Shrestha +5 more
doaj +1 more source
A Protocol of National Mixed‐Methods Assessment of Childhood and Maternal Immunization
ABSTRACT Background and Aims Accurate measurement of routine immunization coverage is essential for detecting immunity gaps, guiding programmatic responses, and supporting equitable vaccine delivery. Iran's Expanded Programme on Immunization has achieved high coverage, but administrative estimates can mask some disparities.
Seyed Aria Nejadghaderi +8 more
wiley +1 more source
Efficacy and Safety of Messenger RNA Vaccines
ABSTRACT Background and Aims The rapid development of mRNA vaccines has revolutionized infectious disease prevention and cancer immunotherapy. While their efficacy is well established, concerns about safety and immunopathological risks persist. This study aims to evaluate the immunogenicity, safety profiles, and design considerations of mRNA vaccines ...
Kesaobaka Batisani, David Chisompola
wiley +1 more source
Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode +4 more
wiley +1 more source
Preclinical and clinical development of preventive rotavirus vaccines: special considerations
INTRODUCTION. Vaccination is recognised as the only effective method for preventing rotavirus disease. Rotavirus remains a leading cause of death in young children, mainly, in developing countries.
A. S. Korovkin +3 more
doaj +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Green Stool Predominance in Babies and Subsequent Bowel Function at 1–2 Years of Age
ABSTRACT Aim To study the relationship between bowel function after birth and at 1–2 years of age in the prospective HELMi cohort of term infants. Methods We focused on infants with predominantly green stools (n = 152) for three consecutive weeks in early life and their sex, age, and delivery mode‐matched controls (n = 300), and evaluated bowel ...
L. Typpö +5 more
wiley +1 more source
The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost
Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost.
Özlem O Gundeslioglu +4 more
doaj +1 more source
The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
Burke, B, Desselberger, U
openaire +3 more sources
Evaluation of Serum Zonulin Levels and Intestinal Permeability in Hidradenitis Suppurativa Patients
ABSTRACT Background Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease. Zonulin is a signaling protein secreted by enterocytes that regulates the function of tight junction complexes and intestinal permeability. The levels of zonulin increase in the blood with the disruption of the intestinal barrier and it is used as a biomarker ...
Elif Çetinkaya +7 more
wiley +1 more source

