Results 71 to 80 of about 48,817 (200)
After the introduction of the rotavirus vaccine, the number of rotavirus-associated deaths and the predicted annual rotavirus detection rate had slightly declined worldwide.
Marlen Martinez-Gutierrez +3 more
doaj +1 more source
This study aims to determine the economic impacts of the major agents causing diarrhoea in newborn calves using Monte Carlo simulation and decision tree analysis. According to the study results, the cost per animal was $13.7 for healthy calves without diarrhoea.
Mehmet Küçükoflaz +7 more
wiley +1 more source
Rotavirus gastroenteritis among children under five years of age in Izmir, Turkey
Little is known about the epidemiology of rotavirus infection in Turkey. The aim of the study was to determine the incidence and clinical significance of rotavirus gastroenteritis, in view of the potentially available prevention by rotavirus ...
Zafer Kurugöl +9 more
doaj
The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
Burke, B, Desselberger, U
openaire +3 more sources
Actinomycin Derivatives: Structural Diversification and Biological Activities
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
BackgroundRotavirus, predominantly of group A, is a major cause of severe diarrhoea worldwide, with the greatest burden falling on young children living in less-developed countries. Vaccines directed against this virus have shown promise in recent trials,
D James Nokes +10 more
doaj +1 more source
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
ABSTRACT Background and Aims Acute watery diarrhea (AWD) remains a major global public health problem, and cholera continues to cause substantial morbidity and mortality in settings with inadequate water, sanitation, and hygiene (WASH). Chattogram, a coastal district of Bangladesh, is particularly vulnerable due to seasonal hydroclimatic changes ...
Immamul Muntasir +10 more
wiley +1 more source
ABSTRACT Background Although the global burden of diarrheal diseases (DDs) among children under 5 years of age has declined substantially over recent decades, sex‐specific disparities and regional heterogeneity across Asia—particularly regarding non‐fatal outcomes—remain insufficiently characterized.
Maedeh Amini +3 more
wiley +1 more source
Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface
Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular diffusion of solutes, ions ...
Tingting Cui +3 more
doaj +1 more source

