Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children 200,000 deaths annually, mostly in low-income countries. Rotavirus primarily infects enterocytes and induces diarrhoea through the destruction of absorptive enterocytes (leading to malabsorption), intestinal secretion stimulated by rotavirus non-structural ...
Sue E Crawford +2 more
exaly +10 more sources
Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets [PDF]
Strong CD4+ T cell-mediated immune protection following rotavirus infection has been observed in animal models, but its relevance in humans remains unclear.
Chikondi Malamba-Banda +10 more
doaj +2 more sources
Equine rotavirus infection. [PDF]
This review briefly describes the virus classification, clinical signs, epidemiology, diagnosis, disinfection, and vaccines related equine group A rotavirus (RVA) infection. Equine RVA is one of the most important pathogens causing diarrhoea in foals. The main transmission route is faecal-oral, and the clinical signs are diarrhoea, fever, lethargy, and
Nemoto M, Matsumura T.
europepmc +4 more sources
Epidemic characteristics and effectiveness of vaccine intervention on rotavirus infection: a real-world observational study in Zhejiang Province, China [PDF]
BackgroundRotavirus infection, the most common cause of infant infectious diarrhoea and related deaths worldwide, has imposed a high disease burden in China, especially in Zhejiang Province.
Ziping Miao +27 more
doaj +2 more sources
Burden of group A rotavirus infection among children with acute diarrhoea in Lambaréné, Gabon [PDF]
Background: Rotaviruses are among the most common causal pathogens of severe dehydrating diarrhoea in children. Little is known about the burden of rotavirus diarrhoea in Gabon.
Bayode Romeo Adegbite +9 more
doaj +2 more sources
Global burden and trends of rotavirus infection-associated deaths from 1990 to 2019: an observational trend study [PDF]
Background Rotavirus is the leading global pathogen of diarrhea-associated mortality and poses a great threat to public health in all age groups. This study aimed to explore the global burden and 30-year change patterns of rotavirus infection-associated ...
Yuxia Du +11 more
doaj +2 more sources
Infant Non-Secretor Histoblood Group Antigen Phenotype Reduces Susceptibility to Both Symptomatic and Asymptomatic Rotavirus Infection [PDF]
The infant non-secretor histoblood group antigen phenotype is associated with reduced risk of symptomatic rotavirus diarrhea, one of the leading global causes of severe pediatric diarrheal disease and mortality.
Benjamin Lee +9 more
doaj +2 more sources
Rotavirus infection-associated central nervous system complications: clinicoradiological features and potential mechanisms [PDF]
Despite the introduction of vaccines in 2006, rotavirus remains one of the most common causes of pediatric gastroenteritis worldwide. While many studies have conclusively shown that rotavirus infection causes gastroenteritis and is associated with ...
Kyung Yeon Lee
doaj +1 more source
Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand
Rotavirus A is a highly contagious virus that causes acute gastroenteritis in humans and a wide variety of animals. In this review, we summarized the information on rotavirus described in the studies in the last decade (2008 to 2021) in Thailand ...
Nutthawadee Jampanil +3 more
doaj +1 more source
White matter injury following rotavirus infection in neonates: new aspects to a forgotten entity, 'fifth day fits'? [PDF]
That rotavirus infection can cause neurological symptoms in young children has been well established. However, it is surprising why rotavirus infection has been overlooked as a cause of neonatal seizures for many years, despite significant research ...
Jung Sook Yeom, Chan-Hoo Park
doaj +1 more source

