Results 111 to 120 of about 696,003 (270)

ADAPTATION OF HUMAN ROTAVIRUS STRAINS OF GROUP A TO THE REPRODUCTION IN PASSAGED CELL CULTURES

open access: yesВопросы вирусологии, 2017
The incidence of rotavirus gastroenteritis in the world still has no tendency to reduction. The development of an effective vaccine would reduce or, in the future, even defeat this highly contagious dangerous disease.
S. A. Kolpakov, E. P. Kolpakova
doaj   +1 more source

Impact of rotavirus vaccine on paediatric rotavirus hospitalisation and intussusception in New Zealand: A retrospective cohort study.

open access: yes, 2020
BACKGROUND:Rotavirus results in a significant burden of hospitalisations and deaths globally. Rotavirus vaccine has been used in New Zealand since July 2014.
McIlhone, Karen A   +3 more
core   +1 more source

Efficacy and Safety of Messenger RNA Vaccines

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims The rapid development of mRNA vaccines has revolutionized infectious disease prevention and cancer immunotherapy. While their efficacy is well established, concerns about safety and immunopathological risks persist. This study aims to evaluate the immunogenicity, safety profiles, and design considerations of mRNA vaccines ...
Kesaobaka Batisani, David Chisompola
wiley   +1 more source

Safety and immunogenicity of a novel oral hexavalent rotavirus vaccine:a phase I clinical trial

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Background Rotavirus infections, prevalent in human populations, are caused mostly by group A viruses. Immunization against rotaviruses in infancy is currently the most effective and economical strategy to prevent rotavirus infection.
Zhi-Wei Wu   +13 more
doaj   +1 more source

Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode   +4 more
wiley   +1 more source

Rotavirus vaccines: a story of success [PDF]

open access: yesClinical Microbiology and Infection, 2015
By January 2015, rotavirus vaccination had been implemented in national vaccination programmes in 75 countries worldwide. Two live oral rotavirus vaccines are internationally available: human, monovalent vaccine and human-bovine pentavalent reassortant vaccine. Since January 2014, another live, oral human-bovine monovalent vaccine has been available in
Kollaritsch, H   +3 more
openaire   +3 more sources

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti‐Tumoral Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther   +12 more
wiley   +1 more source

Preclinical and clinical development of preventive rotavirus vaccines: special considerations

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Vaccination is recognised as the only effective method for preventing rotavirus disease. Rotavirus remains a leading cause of death in young children, mainly, in developing countries.
A. S. Korovkin   +3 more
doaj   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Geographic and Temporal Variations in Immunization Coverage in Nepal: An Ecological Time‐Trend Analysis

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Immunization remains a vital public health intervention in Nepal, yet significant disparities persist. This study evaluates the performance of Nepal's national immunization program by analyzing district‐level vaccination coverage and dropout rates from 2009 to 2022 to identify trends and disparities across different routine ...
Kritika Rana   +6 more
wiley   +1 more source

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