Results 131 to 140 of about 696,003 (270)

Challenges for Rotavirus Vaccines

Virology, 2001
p s a t M i i Last year the rotavirus (RV) field sustained a profound surprise and setback when the first licensed RV vaccine (Rotashield–Wyeth Ayert) was withdrawn from the market because of its temporal association with very rare cases of intestinal intussusception which mostly occurred in the first week after administration of the first vaccine dose
Franco, M.A., Greenberg, H.B.
openaire   +2 more sources

Estimated reductions in hospitalizations and deaths from childhood diarrhea following implementation of rotavirus vaccination in Africa

Expert Review of Vaccines, 2017
Introduction: Rotavirus is the leading cause of hospitalizations and deaths from diarrhea. 33 African countries had introduced rotavirus vaccines by 2016.
Minesh P. Shah, Jacqueline E. Tate, Jason M. Mwenda, A. Duncan Steele, Umesh D. Parashar   +4 more
doaj   +1 more source

Antirotavirus IgA seroconversion rates in children who receive concomitant oral poliovirus vaccine: A secondary, pooled analysis of Phase II and III trial data from 33 countries.

PLoS Medicine, 2019
BackgroundDespite the success of rotavirus vaccines over the last decade, rotavirus remains a leading cause of severe diarrheal disease among young children.
Julia M Baker, Jacqueline E Tate, Juan Leon, Michael J Haber, Benjamin A Lopman   +4 more
doaj   +1 more source

Rotavirus vaccine : what you need to know [PDF]

Rotavirus is a virus that causes diarrhea, mostly in babies and young children. The diarrhea can be severe, and lead to dehydration. Vomiting and fever are also common in babies with rotavirus.Before rotavirus vaccine, rotavirus disease was a common and ...

core   +2 more sources

A Comparison of the Test-negative and Traditional Case-control Study Designs with Respect to the Bias of Estimates of Rotavirus Vaccine Effectiveness

Vaccine, 2018
Estimation of the effectiveness of rotavirus vaccines via the test-negative control study design has gained popularity over the past few years. In this study design, children with severe diarrhea who test positive for rotavirus infection are considered ...
M. Haber, B. Lopman, J. Tate, Meng Shi, U. Parashar   +4 more
semanticscholar   +1 more source

Rotavirus Vaccine and Intussusception

The Journal of Pediatric Pharmacology and Therapeutics, 2007
On February 13, 2007, the Food and Drug Administration (FDA) released a public health notification on RotaTeq (Live, Oral, Pentavalent Vaccine—Merck and Co.) and intussusception.1 The report stated that there were 28 cases of intussusception in the ongoing post-marketing surveillance. Also, this notification stated that the purpose of this notification
openaire   +3 more sources

Rotavirus Burden, Genetic Diversity and Impact of Vaccine in Children under Five in Tanzania

Pathogens, 2019
In Tanzania, rotavirus infections are responsible for 72% of diarrhea deaths in children under five. The Rotarix vaccine was introduced in early 2013 to mitigate rotavirus infections.
Joseph J. Malakalinga, Gerald Misinzo, George M. Msalya, Rudovick R. Kazwala   +3 more
doaj   +1 more source

Profile: The Kilifi Health and Demographic Surveillance System (KHDSS). [PDF]

, 2012
The Kilifi Health and Demographic Surveillance System (KHDSS), located on the Indian Ocean coast of Kenya, was established in 2000 as a record of births, pregnancies, migration events and deaths and is maintained by 4-monthly household visits.
Tsofa, B, H. Gatakaa, Ojal, J, Nyundo, Christopher, Nyundo, C, Moisi, Jennifer C, Peshu, N, Scott, John, J. C. Moisi, Molyneux, CS, F. Kombe, Moisi, JC, Williams, TN, J. Ojal, Kombe, Francis, Bauni, Evasius, J. A. G. Scott, Molyneux, Catherine S, E. Bauni, Peshu, Norbert, C. Nyundo, Tsofa, Benjamin, Marsh, K, N. Peshu, K. Marsh, Ojal, John, B. Tsofa, Scott, JA, Bauni, E, Scott, J Anthony G, Williams, Thomas N, Scott, JAG, Molyneux, Catherine, Williams, Thomas, Kombe, F, Marsh, Kevin, Gatakaa, Hellen, Gatakaa, H, T. N. Williams, C. S. Molyneux   +39 more
core   +1 more source

Novel Universal Recombinant Rotavirus A Vaccine Candidate: Evaluation of Immunological Properties

Viruses
Rotavirus infection is a leading cause of severe dehydrating gastroenteritis in children under 5 years of age. Although rotavirus-associated mortality has decreased considerably because of the introduction of the worldwide rotavirus vaccination, the ...
Dmitriy L. Granovskiy, Nelli S. Khudainazarova, Ekaterina A. Evtushenko, Ekaterina M. Ryabchevskaya, Olga A. Kondakova, Marina V. Arkhipenko, Marina V. Kovrizhko, Elena P. Kolpakova, Tatyana I. Tverdokhlebova, Nikolai A. Nikitin, Olga V. Karpova   +10 more
doaj   +1 more source

Rotavirus vaccine response correlates with the infant gut microbiota composition in Pakistan

Gut microbes, 2017
Rotavirus (RV) is the leading cause of diarrhea-related death in children worldwide and ninety-five percent of rotavirus deaths occur in Africa and Asia.
V. Harris, Asad Ali, S. Fuentes, K. Korpela, M. Kazi, J. Tate, U. Parashar, W. Wiersinga, C. Giaquinto, C. de Weerth, W. D. de Vos   +10 more
semanticscholar   +1 more source