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Zoonotic aspects of rotaviruses
Veterinary Microbiology, 2010 Rotaviruses are important enteric pathogens of humans and animals. Group A rotaviruses (GARVs) account for up to 1 million children deaths each year, chiefly in developing countries and human vaccines are now available in many countries. Rotavirus-associated enteritis is a major problem in livestock animals, notably in young calves and piglets.
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Veterinary Microbiology, 1993
Rotaviruses cause gastroenteritis in neonates of many animal species including cattle, swine, horses, dogs, cats, chickens and turkeys. Rotavirions are nonenveloped, are about 75 nm in diameter, have a double capsid, and contain 11 double-stranded RNA segments as their genome.
P S, Paul, Y S, Lyoo
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Rotaviruses cause gastroenteritis in neonates of many animal species including cattle, swine, horses, dogs, cats, chickens and turkeys. Rotavirions are nonenveloped, are about 75 nm in diameter, have a double capsid, and contain 11 double-stranded RNA segments as their genome.
P S, Paul, Y S, Lyoo
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1983
The Rotavirus genus of the Reoviridae consists of a number of antigenically related and morphologically identical viruses that cause enteritis, primarily in young mammals and avians. The genus was established by the International Committee on Taxonomy of Viruses at the Fourth International Congress for Virology in 1978 (Matthews 1979).
M K, Estes, E L, Palmer, J F, Obijeski
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The Rotavirus genus of the Reoviridae consists of a number of antigenically related and morphologically identical viruses that cause enteritis, primarily in young mammals and avians. The genus was established by the International Committee on Taxonomy of Viruses at the Fourth International Congress for Virology in 1978 (Matthews 1979).
M K, Estes, E L, Palmer, J F, Obijeski
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Carbohydrate recognition by rotaviruses
Journal of Structural and Functional Genomics, 2013Rotaviruses are a global health concern causing severe childhood diarrhea. Though the mechanisms mediating rotavirus cell entry require further characterisation, it is acknowledged that an essential and critical step in rotavirus infection is the virus cell attachment via initial recognition of cell surface carbohydrate-containing receptors.
Yu, X, Blanchard, H
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1989
A potent, multivalent, serotype-specific RV vaccine and improved tests for measuring vaccine potency would help eliminate the necessity to pretest for vaccine efficacy in every country selected for its deployment. Until then, the need will continue for vaccine trials in various countries because the pathogenesis and epidemiology of RV and RV serotypes ...
R, Edelman, J, Flores, A Z, Kapikian
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A potent, multivalent, serotype-specific RV vaccine and improved tests for measuring vaccine potency would help eliminate the necessity to pretest for vaccine efficacy in every country selected for its deployment. Until then, the need will continue for vaccine trials in various countries because the pathogenesis and epidemiology of RV and RV serotypes ...
R, Edelman, J, Flores, A Z, Kapikian
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2003
Rotaviruses (RVs) are the chief etiologic agent of viral gastroenteritis in infants and young children, and in the young of a large variety of animal species. Since the discovery of RVs in man 25 yr ago, much has been learned about their genome and protein composition; their three-dimensional structure; their replication, pathogenesis and clinical ...
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Rotaviruses (RVs) are the chief etiologic agent of viral gastroenteritis in infants and young children, and in the young of a large variety of animal species. Since the discovery of RVs in man 25 yr ago, much has been learned about their genome and protein composition; their three-dimensional structure; their replication, pathogenesis and clinical ...
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Annual Review of Microbiology, 1997
▪ Abstract Genetic analyses have contributed significantly to our understanding of the biology of the rotaviruses. The distinguishing feature of the virus is a genome consisting of 11 segments of double-stranded RNA. The segmented nature of the genome allows reassortment of genome segments during mixed infections, which is the major distinguishing ...
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▪ Abstract Genetic analyses have contributed significantly to our understanding of the biology of the rotaviruses. The distinguishing feature of the virus is a genome consisting of 11 segments of double-stranded RNA. The segmented nature of the genome allows reassortment of genome segments during mixed infections, which is the major distinguishing ...
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Genome rearrangements of rotaviruses
1996Rotaviruses (and other members of the Reoviridae family) undergo rearrangements of their genomes. This review describes evidence of rearranged genomes in rotaviruses. Their structure and functions are reviewed. Possible mechanisms of their emergence are discussed, and the significance of genome rearrangements for viral evolution is considered.
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Molecular Biology of Rotaviruses
1990Publisher Summary This chapter highlights unique aspects of the rotavirus replication cycle, to review recent work on the molecular biology of group A rotaviruses, and to indicate those areas in which the knowledge is incomplete. A summary of the nonstructural proteins and the structural polypeptides known to represent genuine components of the SA11 ...
A R, Bellamy, G W, Both
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